STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cts7Cathepsin 7; Involved in trophoblast cell proliferation and differentiation probably by affecting mitotic cell cycle progression. Proteolytic activity and nuclear localization are essential for its role in cell cycle progression (By similarity). Belongs to the peptidase C1 family. (331 aa)    
Predicted Functional Partners:
Prl7b1
Prolactin-7B1.
   
  
 0.578
Pappa2
Pappalysin 2.
      
 0.576
Shd
Similar to src homology 2 domain-containing transforming protein D.
      
 0.571
Prl3d4
Prolactin-3D4.
   
  
 0.563
Ceacam3
Carcinoembryonic antigen-related cell adhesion molecule 3; Possibly involved in cell adhesion.
   
 
 0.556
Prl8a9
Prolactin-8A9; Belongs to the somatotropin/prolactin family.
   
  
 0.554
Cgm4
Carcinoembryonic antigen gene family 4.
   
 
 0.551
Amn
Amnion-associated transmembrane protein.
      
 0.499
Rnf17
Ring finger protein 17.
      
 0.494
Rnf103
E3 ubiquitin-protein ligase RNF103; Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway.
   
  
 0.482
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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