node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cmpk2 | Ddx58 | ENSRNOP00000043468 | ENSRNOP00000057492 | Cytidine/uridine monophosphate kinase 2. | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | 0.507 |
Cmpk2 | Ifi44 | ENSRNOP00000043468 | ENSRNOP00000071211 | Cytidine/uridine monophosphate kinase 2. | Interferon-induced protein 44, isoform CRA_a. | 0.726 |
Cmpk2 | Ifih1 | ENSRNOP00000043468 | ENSRNOP00000009621 | Cytidine/uridine monophosphate kinase 2. | Interferon-induced with helicase C domain 1. | 0.766 |
Cmpk2 | Ifit1 | ENSRNOP00000043468 | ENSRNOP00000025770 | Cytidine/uridine monophosphate kinase 2. | Interferon-induced protein with tetratricopeptide repeats 1. | 0.759 |
Cmpk2 | Ifit2 | ENSRNOP00000043468 | ENSRNOP00000051639 | Cytidine/uridine monophosphate kinase 2. | Interferon-induced protein with tetratricopeptide repeats 2. | 0.848 |
Cmpk2 | Isg15 | ENSRNOP00000043468 | ENSRNOP00000035405 | Cytidine/uridine monophosphate kinase 2. | Interferon, alpha-inducible protein (Clone IFI-15K) (Predicted). | 0.663 |
Cmpk2 | Oasl | ENSRNOP00000043468 | ENSRNOP00000001570 | Cytidine/uridine monophosphate kinase 2. | 2'-5'-oligoadenylate synthase-like protein 1; Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity via an alternative antiviral pathway independent of RNase L (By similarity). | 0.719 |
Cmpk2 | Oasl2 | ENSRNOP00000043468 | ENSRNOP00000001600 | Cytidine/uridine monophosphate kinase 2. | 2'-5'-oligoadenylate synthase-like protein 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. Synthesizes oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent p [...] | 0.592 |
Cmpk2 | Rsad2 | ENSRNOP00000043468 | ENSRNOP00000010092 | Cytidine/uridine monophosphate kinase 2. | Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, thro [...] | 0.965 |
Cmpk2 | Stat1 | ENSRNOP00000043468 | ENSRNOP00000070183 | Cytidine/uridine monophosphate kinase 2. | Signal transducer and activator of transcription. | 0.509 |
Ddx58 | Cmpk2 | ENSRNOP00000057492 | ENSRNOP00000043468 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Cytidine/uridine monophosphate kinase 2. | 0.507 |
Ddx58 | Ifi44 | ENSRNOP00000057492 | ENSRNOP00000071211 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Interferon-induced protein 44, isoform CRA_a. | 0.947 |
Ddx58 | Ifih1 | ENSRNOP00000057492 | ENSRNOP00000009621 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Interferon-induced with helicase C domain 1. | 0.852 |
Ddx58 | Ifit1 | ENSRNOP00000057492 | ENSRNOP00000025770 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Interferon-induced protein with tetratricopeptide repeats 1. | 0.876 |
Ddx58 | Ifit2 | ENSRNOP00000057492 | ENSRNOP00000051639 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Interferon-induced protein with tetratricopeptide repeats 2. | 0.884 |
Ddx58 | Isg15 | ENSRNOP00000057492 | ENSRNOP00000035405 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Interferon, alpha-inducible protein (Clone IFI-15K) (Predicted). | 0.995 |
Ddx58 | Oasl | ENSRNOP00000057492 | ENSRNOP00000001570 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | 2'-5'-oligoadenylate synthase-like protein 1; Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity via an alternative antiviral pathway independent of RNase L (By similarity). | 0.847 |
Ddx58 | Oasl2 | ENSRNOP00000057492 | ENSRNOP00000001600 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | 2'-5'-oligoadenylate synthase-like protein 2; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. Synthesizes oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent p [...] | 0.904 |
Ddx58 | Rsad2 | ENSRNOP00000057492 | ENSRNOP00000010092 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, thro [...] | 0.908 |
Ddx58 | Stat1 | ENSRNOP00000057492 | ENSRNOP00000070183 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Signal transducer and activator of transcription. | 0.916 |