node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Apip | Fam220a | ENSRNOP00000009797 | ENSRNOP00000059765 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | Protein FAM220A; May negatively regulate STAT3. | 0.496 |
Apip | Myadml2 | ENSRNOP00000009797 | ENSRNOP00000051831 | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | Myeloid-associated differentiation marker-like protein 2. | 0.475 |
Cmtm8 | Myadml2 | ENSRNOP00000015188 | ENSRNOP00000051831 | CKLF-like MARVEL transmembrane domain containing 8, isoform CRA_b. | Myeloid-associated differentiation marker-like protein 2. | 0.534 |
Cuzd1 | Myadml2 | ENSRNOP00000045430 | ENSRNOP00000051831 | CUB and zona pellucida-like domain-containing protein 1; CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may play a role in these processes. May play a role in trypsin activation in pancreatic acinar cells. May also play a role in the uterus during late pregnancy (By similarity). | Myeloid-associated differentiation marker-like protein 2. | 0.536 |
Fam220a | Apip | ENSRNOP00000059765 | ENSRNOP00000009797 | Protein FAM220A; May negatively regulate STAT3. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | 0.496 |
Fam220a | Myadml2 | ENSRNOP00000059765 | ENSRNOP00000051831 | Protein FAM220A; May negatively regulate STAT3. | Myeloid-associated differentiation marker-like protein 2. | 0.576 |
Fam220a | Yeats4 | ENSRNOP00000059765 | ENSRNOP00000007580 | Protein FAM220A; May negatively regulate STAT3. | YEATS domain containing 4 (Predicted), isoform CRA_b. | 0.532 |
Kctd19 | Myadml2 | ENSRNOP00000022497 | ENSRNOP00000051831 | Potassium channel tetramerization domain-containing 19. | Myeloid-associated differentiation marker-like protein 2. | 0.550 |
Lmf1 | Myadml2 | ENSRNOP00000000246 | ENSRNOP00000051831 | Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. | Myeloid-associated differentiation marker-like protein 2. | 0.479 |
Lmf1 | Pcyt2 | ENSRNOP00000000246 | ENSRNOP00000051835 | Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine (By similarity); Belongs to the cytidylyltransferase family. | 0.519 |
Mal | Myadml2 | ENSRNOP00000020870 | ENSRNOP00000051831 | Myelin and lymphocyte protein; Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function; Belongs to the MAL family. | Myeloid-associated differentiation marker-like protein 2. | 0.448 |
Mall | Myadml2 | ENSRNOP00000021082 | ENSRNOP00000051831 | Mal, T-cell differentiation protein-like. | Myeloid-associated differentiation marker-like protein 2. | 0.610 |
Myadml2 | Apip | ENSRNOP00000051831 | ENSRNOP00000009797 | Myeloid-associated differentiation marker-like protein 2. | Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response (pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death; Belongs to the aldolase class II family. MtnB subfamily. | 0.475 |
Myadml2 | Cmtm8 | ENSRNOP00000051831 | ENSRNOP00000015188 | Myeloid-associated differentiation marker-like protein 2. | CKLF-like MARVEL transmembrane domain containing 8, isoform CRA_b. | 0.534 |
Myadml2 | Cuzd1 | ENSRNOP00000051831 | ENSRNOP00000045430 | Myeloid-associated differentiation marker-like protein 2. | CUB and zona pellucida-like domain-containing protein 1; CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may play a role in these processes. May play a role in trypsin activation in pancreatic acinar cells. May also play a role in the uterus during late pregnancy (By similarity). | 0.536 |
Myadml2 | Fam220a | ENSRNOP00000051831 | ENSRNOP00000059765 | Myeloid-associated differentiation marker-like protein 2. | Protein FAM220A; May negatively regulate STAT3. | 0.576 |
Myadml2 | Kctd19 | ENSRNOP00000051831 | ENSRNOP00000022497 | Myeloid-associated differentiation marker-like protein 2. | Potassium channel tetramerization domain-containing 19. | 0.550 |
Myadml2 | Lmf1 | ENSRNOP00000051831 | ENSRNOP00000000246 | Myeloid-associated differentiation marker-like protein 2. | Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. | 0.479 |
Myadml2 | Mal | ENSRNOP00000051831 | ENSRNOP00000020870 | Myeloid-associated differentiation marker-like protein 2. | Myelin and lymphocyte protein; Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function; Belongs to the MAL family. | 0.448 |
Myadml2 | Mall | ENSRNOP00000051831 | ENSRNOP00000021082 | Myeloid-associated differentiation marker-like protein 2. | Mal, T-cell differentiation protein-like. | 0.610 |