node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Defb1 | Defb17 | ENSRNOP00000018428 | ENSRNOP00000057521 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | 0.515 |
Defb1 | Defb24 | ENSRNOP00000018428 | ENSRNOP00000052276 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin 24. | 0.853 |
Defb1 | Defb25 | ENSRNOP00000018428 | ENSRNOP00000052274 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin 25; Has antibacterial activity; Belongs to the beta-defensin family. | 0.617 |
Defb1 | Defb27 | ENSRNOP00000018428 | ENSRNOP00000052275 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | 0.532 |
Defb1 | Defb30 | ENSRNOP00000018428 | ENSRNOP00000055981 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin 30; Has antibacterial activity; Belongs to the beta-defensin family. | 0.633 |
Defb1 | Defb36 | ENSRNOP00000018428 | ENSRNOP00000009930 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | 0.658 |
Defb1 | Defb4 | ENSRNOP00000018428 | ENSRNOP00000054838 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells. | 0.992 |
Defb1 | Defb42 | ENSRNOP00000018428 | ENSRNOP00000055986 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin 42. | 0.572 |
Defb1 | Defb44 | ENSRNOP00000018428 | ENSRNOP00000055979 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Beta-defensin 44, isoform CRA_b. | 0.690 |
Defb1 | Spag11a | ENSRNOP00000018428 | ENSRNOP00000018741 | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | Sperm-associated antigen 11; Antimicrobial peptide against E.coli. Is also responsible for sperm maturation, storage, and protection. Belongs to the beta-defensin family. | 0.535 |
Defb17 | Defb1 | ENSRNOP00000057521 | ENSRNOP00000018428 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family. | 0.515 |
Defb17 | Defb24 | ENSRNOP00000057521 | ENSRNOP00000052276 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin 24. | 0.722 |
Defb17 | Defb25 | ENSRNOP00000057521 | ENSRNOP00000052274 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin 25; Has antibacterial activity; Belongs to the beta-defensin family. | 0.623 |
Defb17 | Defb27 | ENSRNOP00000057521 | ENSRNOP00000052275 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | 0.548 |
Defb17 | Defb30 | ENSRNOP00000057521 | ENSRNOP00000055981 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin 30; Has antibacterial activity; Belongs to the beta-defensin family. | 0.768 |
Defb17 | Defb36 | ENSRNOP00000057521 | ENSRNOP00000009930 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family. | 0.550 |
Defb17 | Defb4 | ENSRNOP00000057521 | ENSRNOP00000054838 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells. | 0.430 |
Defb17 | Defb42 | ENSRNOP00000057521 | ENSRNOP00000055986 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin 42. | 0.758 |
Defb17 | Defb44 | ENSRNOP00000057521 | ENSRNOP00000055979 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Beta-defensin 44, isoform CRA_b. | 0.781 |
Defb17 | Spag11a | ENSRNOP00000057521 | ENSRNOP00000018741 | Beta-defensin 17; Has antibacterial activity; Belongs to the beta-defensin family. | Sperm-associated antigen 11; Antimicrobial peptide against E.coli. Is also responsible for sperm maturation, storage, and protection. Belongs to the beta-defensin family. | 0.534 |