STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gpr157G-protein coupled receptor 157; Orphan receptor that promotes neuronal differentiation of radial glial progenitors (RGPs). The activity of this receptor is mediated by a G(q)-protein that activates a phosphatidylinositol- calcium second messenger; Belongs to the G-protein coupled receptor 2 family. (330 aa)    
Predicted Functional Partners:
Tmem185a
Transmembrane protein 185A.
      
 0.694
Gpr137c
G protein-coupled receptor 137C.
      
 0.654
Qrfpr
Pyroglutamylated RF-amide peptide receptor; Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels.
      
 0.618
Pgr15l
Similar to G protein-coupled receptor PGR15L (Predicted); Belongs to the G-protein coupled receptor 1 family.
      
 0.613
Adgrd1
Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.588
Lzic
Protein LZIC.
    
 
 0.568
Paqr5
Progestin and adipoQ receptor family member 5.
      
 0.552
Gpr149
Probable G-protein coupled receptor 149; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.545
Tulp3
Tubby-like protein; Belongs to the TUB family.
      
 0.534
Gpr107
Protein GPR107; Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor. Involved in blood sugar regulation through the induction of glucagon in response to low glucose. Belongs to the LU7TM family.
      
 0.526
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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