node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bub1 | Fzr1 | ENSRNOP00000042114 | ENSRNOP00000005624 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Fizzy/cell division cycle 20 related 1 (Drosophila) (Predicted), isoform CRA_a. | 0.797 |
Bub1 | Mad2l1 | ENSRNOP00000042114 | ENSRNOP00000007285 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | 0.998 |
Bub1 | Mad2l2 | ENSRNOP00000042114 | ENSRNOP00000052521 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | 0.937 |
Bub1 | Pole | ENSRNOP00000042114 | ENSRNOP00000058920 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.488 |
Fzr1 | Bub1 | ENSRNOP00000005624 | ENSRNOP00000042114 | Fizzy/cell division cycle 20 related 1 (Drosophila) (Predicted), isoform CRA_a. | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | 0.797 |
Fzr1 | Mad2l1 | ENSRNOP00000005624 | ENSRNOP00000007285 | Fizzy/cell division cycle 20 related 1 (Drosophila) (Predicted), isoform CRA_a. | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | 0.989 |
Fzr1 | Mad2l2 | ENSRNOP00000005624 | ENSRNOP00000052521 | Fizzy/cell division cycle 20 related 1 (Drosophila) (Predicted), isoform CRA_a. | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | 0.937 |
Mad2l1 | Bub1 | ENSRNOP00000007285 | ENSRNOP00000042114 | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | 0.998 |
Mad2l1 | Fzr1 | ENSRNOP00000007285 | ENSRNOP00000005624 | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | Fizzy/cell division cycle 20 related 1 (Drosophila) (Predicted), isoform CRA_a. | 0.989 |
Mad2l1 | Mad2l2 | ENSRNOP00000007285 | ENSRNOP00000052521 | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | 0.958 |
Mad2l1 | Pola1 | ENSRNOP00000007285 | ENSRNOP00000018147 | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | DNA polymerase alpha catalytic subunit; Catalytic subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, a regulatory subunit POLA2 and two primase subunits PRIM1 and PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA p [...] | 0.550 |
Mad2l1 | Pold1 | ENSRNOP00000007285 | ENSRNOP00000026797 | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol- delta4), displays differences in catalytic activity. Most notably, expresses higher pro [...] | 0.510 |
Mad2l1 | Pole | ENSRNOP00000007285 | ENSRNOP00000058920 | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.482 |
Mad2l1 | Rev3l | ENSRNOP00000007285 | ENSRNOP00000054053 | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | REV3-like, DNA directed polymerase zeta catalytic subunit. | 0.468 |
Mad2l2 | Bub1 | ENSRNOP00000052521 | ENSRNOP00000042114 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | 0.937 |
Mad2l2 | Fzr1 | ENSRNOP00000052521 | ENSRNOP00000005624 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | Fizzy/cell division cycle 20 related 1 (Drosophila) (Predicted), isoform CRA_a. | 0.937 |
Mad2l2 | Mad2l1 | ENSRNOP00000052521 | ENSRNOP00000007285 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | MAD2 (Mitotic arrest deficient, homolog)-like 1 (Yeast) (Predicted), isoform CRA_a. | 0.958 |
Mad2l2 | Pola1 | ENSRNOP00000052521 | ENSRNOP00000018147 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | DNA polymerase alpha catalytic subunit; Catalytic subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, a regulatory subunit POLA2 and two primase subunits PRIM1 and PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA p [...] | 0.938 |
Mad2l2 | Pold1 | ENSRNOP00000052521 | ENSRNOP00000026797 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | DNA polymerase delta catalytic subunit; As the catalytic component of the trimeric (Pol-delta3 complex) and tetrameric DNA polymerase delta complexes (Pol-delta4 complex), plays a crucial role in high fidelity genome replication, including in lagging strand synthesis, and repair. Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities. Requires the presence of accessory proteins POLD2, POLD3 and POLD4 for full activity. Depending upon the absence (Pol-delta3) or the presence of POLD4 (Pol- delta4), displays differences in catalytic activity. Most notably, expresses higher pro [...] | 0.953 |
Mad2l2 | Pold2 | ENSRNOP00000052521 | ENSRNOP00000072093 | Mitotic spindle assembly checkpoint protein MAD2B; Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks [...] | DNA polymerase delta subunit 2; Accessory component of both the DNA polymerase delta complex and the DNA polymerase zeta complex. As a component of the trimeric and tetrameric DNA polymerase delta complexes (Pol-delta3 and Pol-delta4, respectively), plays a role in high fidelity genome replication, including in lagging strand synthesis, and repair. Pol-delta3 and Pol- delta4 are characterized by the absence or the presence of POLD4. They exhibit differences in catalytic activity. Most notably, Pol-delta3 shows higher proofreading activity than Pol-delta4. Although both Pol- delta3 and [...] | 0.991 |