STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tgm4Protein-glutamine gamma-glutamyltransferase 4; Associated with the mammalian reproductive process. Plays an important role in the formation of the seminal coagulum through the cross-linking of specific proteins present in the seminal plasma. Transglutaminase is also required to stabilize the copulatory plug. (667 aa)    
Predicted Functional Partners:
Pate4
Seminal vesicle protein, secretion 7 (Predicted).
   
  
 0.816
Semg1
Seminal vesicle secretory protein 2; The rat seminal vesicle contains six major androgen-dependent secretory proteins referred to as SVS I-VI. The SVS I-III proteins appear to be components of the rat copulatory plug, with the SVS II protein being the major component.
   
  
 0.738
Msmb
Beta-microseminoprotein; Belongs to the beta-microseminoprotein family.
   
  
 0.727
LOC103691965-2
Seminal vesicle secretory protein 4.
   
  
 0.727
Svs1
Amine oxidase; Belongs to the copper/topaquinone oxidase family.
   
  
 0.698
Svs4
Seminal vesicle secretory protein 4.
   
  
 0.682
LOC103691966
Seminal vesicle secretory protein 2-like.
   
  
 0.665
LOC103691965
Seminal vesicle secretory protein 4.
   
  
 0.662
Acpp
Prostatic acid phosphatase; A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins. Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (By similarity).
      
 0.652
Svs3b
Seminal vesicle secretory protein 3A.
   
  
 0.643
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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