STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spata22Spermatogenesis-associated 22. (361 aa)    
Predicted Functional Partners:
Meiob
Meiosis-specific with OB domain-containing protein; Single-stranded DNA-binding protein required for homologous recombination in meiosis I. Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis. Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage. May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination. Displays Single-stranded DNA 3'-5' exonuclease activity i [...]
      
 0.949
Shpk
Carbohydrate kinase-like, isoform CRA_b.
      
 0.823
Syce3
Synaptonemal complex central element protein 3.
      
 0.781
Hsf2bp
Similar to heat shock transcription factor 2 binding protein (Predicted).
      
 0.728
Olr1470
Olfactory receptor-like protein I9; Odorant receptor.
      
 0.697
Olr1470-2
Olfactory receptor.
      
 0.697
Olr1468
Olfactory receptor 1468; Odorant receptor.
      
 0.696
Olr1466
Olfactory receptor.
      
 0.696
Olr1471
Olfactory receptor.
      
 0.696
Olr1469
Olfactory receptor 1; Odorant receptor. Activated by a lily-derived aldehyde as well as other odorants. May signal through an inositol 1,4,5- trisphosphate (IP3) second messenger system.
      
 0.695
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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