node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ddx58 | Ifi35 | ENSRNOP00000057492 | ENSRNOP00000028067 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Interferon-induced protein 35, isoform CRA_a. | 0.692 |
Ddx58 | Irf7 | ENSRNOP00000057492 | ENSRNOP00000023504 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Interferon regulatory factor 7. | 0.900 |
Ddx58 | Oas1a | ENSRNOP00000057492 | ENSRNOP00000036734 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | 2'-5'-oligoadenylate synthase 1A; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | 0.751 |
Ddx58 | Parp9 | ENSRNOP00000057492 | ENSRNOP00000033812 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Poly [ADP-ribose] polymerase. | 0.821 |
Ddx58 | Sp110 | ENSRNOP00000057492 | ENSRNOP00000053828 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Sp110 nuclear body protein; May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells (By similarity). | 0.655 |
Ddx58 | Stat1 | ENSRNOP00000057492 | ENSRNOP00000070183 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | Signal transducer and activator of transcription. | 0.916 |
Ifi35 | Ddx58 | ENSRNOP00000028067 | ENSRNOP00000057492 | Interferon-induced protein 35, isoform CRA_a. | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | 0.692 |
Ifi35 | Irf7 | ENSRNOP00000028067 | ENSRNOP00000023504 | Interferon-induced protein 35, isoform CRA_a. | Interferon regulatory factor 7. | 0.841 |
Ifi35 | Oas1a | ENSRNOP00000028067 | ENSRNOP00000036734 | Interferon-induced protein 35, isoform CRA_a. | 2'-5'-oligoadenylate synthase 1A; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | 0.669 |
Ifi35 | Parp9 | ENSRNOP00000028067 | ENSRNOP00000033812 | Interferon-induced protein 35, isoform CRA_a. | Poly [ADP-ribose] polymerase. | 0.832 |
Ifi35 | Sp110 | ENSRNOP00000028067 | ENSRNOP00000053828 | Interferon-induced protein 35, isoform CRA_a. | Sp110 nuclear body protein; May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells (By similarity). | 0.663 |
Ifi35 | Stat1 | ENSRNOP00000028067 | ENSRNOP00000070183 | Interferon-induced protein 35, isoform CRA_a. | Signal transducer and activator of transcription. | 0.799 |
Irf7 | Ddx58 | ENSRNOP00000023504 | ENSRNOP00000057492 | Interferon regulatory factor 7. | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | 0.900 |
Irf7 | Ifi35 | ENSRNOP00000023504 | ENSRNOP00000028067 | Interferon regulatory factor 7. | Interferon-induced protein 35, isoform CRA_a. | 0.841 |
Irf7 | Oas1a | ENSRNOP00000023504 | ENSRNOP00000036734 | Interferon regulatory factor 7. | 2'-5'-oligoadenylate synthase 1A; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | 0.888 |
Irf7 | Parp9 | ENSRNOP00000023504 | ENSRNOP00000033812 | Interferon regulatory factor 7. | Poly [ADP-ribose] polymerase. | 0.572 |
Irf7 | Sp110 | ENSRNOP00000023504 | ENSRNOP00000053828 | Interferon regulatory factor 7. | Sp110 nuclear body protein; May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells (By similarity). | 0.505 |
Irf7 | Stat1 | ENSRNOP00000023504 | ENSRNOP00000070183 | Interferon regulatory factor 7. | Signal transducer and activator of transcription. | 0.908 |
Oas1a | Ddx58 | ENSRNOP00000036734 | ENSRNOP00000057492 | 2'-5'-oligoadenylate synthase 1A; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 (Predicted). | 0.751 |
Oas1a | Ifi35 | ENSRNOP00000036734 | ENSRNOP00000028067 | 2'-5'-oligoadenylate synthase 1A; Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition [...] | Interferon-induced protein 35, isoform CRA_a. | 0.669 |