STRINGSTRING
Grina protein (Rattus norvegicus) - STRING interaction network
"Grina" - Protein lifeguard 1 in Rattus norvegicus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GrinaProtein lifeguard 1; Potential apoptotic regulator (348 aa)    
Predicted Functional Partners:
Syf2
Pre-mRNA-splicing factor SYF2; May be involved in pre-mRNA splicing (242 aa)
           
  0.649
Gpr19
Probable G-protein coupled receptor 19; Orphan receptor (415 aa)
           
  0.627
Clptm1
Cleft lip and palate associated transmembrane protein 1 (664 aa)
     
        0.627
Pde6a
Phosphodiesterase 6A, cGMP-specific, rod, alpha (860 aa)
           
  0.622
Cyhr1
Cysteine/histidine-rich 1 (311 aa)
     
   
  0.621
Mpp1
Uncharacterized protein (319 aa)
     
        0.616
Asb6
Ankyrin repeat and SOCS box-containing 6 (345 aa)
     
   
  0.615
Grin2d
Glutamate receptor ionotropic, NMDA 2D; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2D/GRIN2D subfamily (1357 aa)
     
   
  0.603
Ktn1
Kinectin 1 (kinesin receptor) (1325 aa)
           
  0.602
Dag1
Dystroglycan 1 (dystrophin-associated glycoprotein 1) (893 aa)
           
  0.553
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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