STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Defb18Beta-defensin 18; Has antibacterial activity; Belongs to the beta-defensin family. (85 aa)    
Predicted Functional Partners:
Defb39
Beta-defensin 39; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.898
Defb25
Beta-defensin 25; Has antibacterial activity; Belongs to the beta-defensin family.
  
  
 0.894
Defb30
Beta-defensin 30; Has antibacterial activity; Belongs to the beta-defensin family.
  
 
 0.891
Defb44
Beta-defensin 44, isoform CRA_b.
  
 
 0.889
Defb24
Beta-defensin 24.
     
 0.715
Defb42
Beta-defensin 42.
  
 
 0.711
RT1-S3
RT1 class Ib, locus S3; Belongs to the MHC class I family.
      
 0.670
Defb20
Beta-defensin 20; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.665
Spag11a
Sperm-associated antigen 11; Antimicrobial peptide against E.coli. Is also responsible for sperm maturation, storage, and protection. Belongs to the beta-defensin family.
   
  
 0.664
Defb41
Beta-defensin 41.
  
  
  0.652
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.