STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prss22Protease, serine, 22 (Predicted); Belongs to the peptidase S1 family. (307 aa)    
Predicted Functional Partners:
Fam183a
Family with sequence similarity 183 member A.
    
 
 0.636
Prr12
Proline-rich 12.
      
 0.497
Kcnu1
Potassium calcium-activated channel subfamily U member 1.
      
 0.479
Cyp2s1
Cytochrome P450, family 2, subfamily s, polypeptide 1.
   
 
 0.439
Ccdc33
Coiled-coil domain-containing protein 33.
    
 
 0.436
Arhgef16
Rho guanine nucleotide exchange factor 16.
   
  
 0.424
Eps8l1
EPS8-like 1 (Predicted).
   
  
 0.421
Stap2
Signal transducing adaptor family member 2.
      
 0.414
RGD1563962
RAB interacting factor.
   
  
 0.401
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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