node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Btbd10 | Kctd1 | ENSRNOP00000070965 | ENSRNOP00000058222 | BTB domain-containing 10. | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | 0.626 |
Btbd10 | Kctd5 | ENSRNOP00000070965 | ENSRNOP00000073503 | BTB domain-containing 10. | BTB/POZ domain-containing protein KCTD5; Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (By similarity). Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity). | 0.496 |
Ccdc34 | Kctd1 | ENSRNOP00000061260 | ENSRNOP00000058222 | Similar to 2810027O19Rik protein (Predicted), isoform CRA_a. | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | 0.474 |
Kctd1 | Btbd10 | ENSRNOP00000058222 | ENSRNOP00000070965 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | BTB domain-containing 10. | 0.626 |
Kctd1 | Ccdc34 | ENSRNOP00000058222 | ENSRNOP00000061260 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | Similar to 2810027O19Rik protein (Predicted), isoform CRA_a. | 0.474 |
Kctd1 | Kctd2 | ENSRNOP00000058222 | ENSRNOP00000059246 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | Potassium channel tetramerization domain-containing 2. | 0.614 |
Kctd1 | Kctd5 | ENSRNOP00000058222 | ENSRNOP00000073503 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | BTB/POZ domain-containing protein KCTD5; Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (By similarity). Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity). | 0.612 |
Kctd1 | LOC102553386 | ENSRNOP00000058222 | ENSRNOP00000075659 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | SUMO-conjugating enzyme UBC9-like. | 0.720 |
Kctd1 | Tfap2a | ENSRNOP00000058222 | ENSRNOP00000040925 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | Transcription factor AP-2-alpha; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and c-Myc. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITE [...] | 0.813 |
Kctd1 | Tfap2b | ENSRNOP00000058222 | ENSRNOP00000075514 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | Transcription factor AP-2 beta. | 0.745 |
Kctd1 | Tfap2c | ENSRNOP00000058222 | ENSRNOP00000006991 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | Transcription factor AP-2, gamma. | 0.738 |
Kctd1 | Tfap2e | ENSRNOP00000058222 | ENSRNOP00000032823 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | Transcription factor AP-2 epsilon. | 0.674 |
Kctd1 | Ube2i | ENSRNOP00000058222 | ENSRNOP00000024406 | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2 and SUMO3 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451 (By similarity). Can catalyze the formation of poly-SUMO chains (By similarity). Essential for nuclear architecture and chromosome segregation (By similarity). Necessary for sumoylation of FOXL2 and KAT5 (By similarity). Sumoylates p53/TP53 at 'Lys-386' (By similarity). Mediates sumoylation of ERCC6 which is essential for its transcription-coupled [...] | 0.761 |
Kctd2 | Kctd1 | ENSRNOP00000059246 | ENSRNOP00000058222 | Potassium channel tetramerization domain-containing 2. | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | 0.614 |
Kctd2 | Kctd5 | ENSRNOP00000059246 | ENSRNOP00000073503 | Potassium channel tetramerization domain-containing 2. | BTB/POZ domain-containing protein KCTD5; Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (By similarity). Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity). | 0.728 |
Kctd5 | Btbd10 | ENSRNOP00000073503 | ENSRNOP00000070965 | BTB/POZ domain-containing protein KCTD5; Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (By similarity). Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity). | BTB domain-containing 10. | 0.496 |
Kctd5 | Kctd1 | ENSRNOP00000073503 | ENSRNOP00000058222 | BTB/POZ domain-containing protein KCTD5; Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (By similarity). Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity). | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | 0.612 |
Kctd5 | Kctd2 | ENSRNOP00000073503 | ENSRNOP00000059246 | BTB/POZ domain-containing protein KCTD5; Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex (By similarity). Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4 (By similarity). | Potassium channel tetramerization domain-containing 2. | 0.728 |
LOC102553386 | Kctd1 | ENSRNOP00000075659 | ENSRNOP00000058222 | SUMO-conjugating enzyme UBC9-like. | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | 0.720 |
Tfap2a | Kctd1 | ENSRNOP00000040925 | ENSRNOP00000058222 | Transcription factor AP-2-alpha; Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and c-Myc. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITE [...] | BTB/POZ domain-containing protein KCTD1; May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent. | 0.813 |