STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cmtm2aCKLF-like MARVEL transmembrane domain-containing 2A. (167 aa)    
Predicted Functional Partners:
Cmtm4
CKLF-like MARVEL transmembrane domain-containing 4.
   
  
 0.671
Cmtm5
Chemokine-like factor super family 5 (Predicted), isoform CRA_b.
      
 0.618
Spesp1
Sperm equatorial segment protein 1; Involved in fertilization ability of sperm.
  
    0.548
Bpifa2
BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
  
   0.532
LOC102552920
Armadillo repeat-containing, X-linked 5.
  
     0.521
M0RCU0_RAT
BPI1 domain-containing protein.
  
 
   0.511
Ltb4r2
Leukotriene B4 receptor 2; Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
   
  
 0.510
Ccr1l1
Chemokine (C-C motif) receptor 1-like 1 (Predicted); Belongs to the G-protein coupled receptor 1 family.
      
 0.504
Ccdc178
Coiled-coil domain-containing 178.
  
    0.500
Vcan
Versican core protein; May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
  
     0.497
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.