STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Igsf11Immunoglobulin superfamily member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth (By similarity). (428 aa)    
Predicted Functional Partners:
Vsir
V-set immunoregulatory receptor.
     
 0.927
Rev3l
REV3-like, DNA directed polymerase zeta catalytic subunit.
      
 0.613
Ccdc74a
Coiled-coil domain-containing 74A.
      
 0.539
Sdsl
Serine dehydratase-like (Predicted).
   
  
 0.507
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain-containing 2.
  
     0.507
Wfikkn1
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1; Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease- inhibitor activity (By similarity).
  
     0.484
Lrrtm4
Leucine-rich repeat transmembrane neuronal protein 4; May play a role in the development and maintenance of the nervous system (By similarity). Exhibits strong synaptogenic activity, restricted to excitatory presynaptic differentiation; Belongs to the LRRTM family.
   
  
 0.466
Lrrc23
Leucine rich repeat containing 23, isoform CRA_a.
      
 0.464
LOC100911585
Leucine rich repeat containing 23.
      
 0.464
Ildr1
Immunoglobulin-like domain-containing receptor 1.
  
   
 0.460
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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