node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Echdc1 | Naxd | ENSRNOP00000015440 | ENSRNOP00000060397 | Ethylmalonyl-CoA decarboxylase; Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level; Belongs to the enoyl-CoA hydratase/isomerase family. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.647 |
Echdc1 | Naxe | ENSRNOP00000015440 | ENSRNOP00000025986 | Ethylmalonyl-CoA decarboxylase; Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level; Belongs to the enoyl-CoA hydratase/isomerase family. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.540 |
Edc3 | Gart | ENSRNOP00000026492 | ENSRNOP00000033253 | Enhancer of mRNA-decapping 3. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.589 |
Edc3 | Naxd | ENSRNOP00000026492 | ENSRNOP00000060397 | Enhancer of mRNA-decapping 3. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.794 |
Edc3 | Nudt14 | ENSRNOP00000026492 | ENSRNOP00000019550 | Enhancer of mRNA-decapping 3. | Nudix (Nucleoside diphosphate linked moiety X)-type motif 14 (Predicted). | 0.474 |
Edc3 | Sdhb | ENSRNOP00000026492 | ENSRNOP00000010593 | Enhancer of mRNA-decapping 3. | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). | 0.482 |
Gart | Edc3 | ENSRNOP00000033253 | ENSRNOP00000026492 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Enhancer of mRNA-decapping 3. | 0.589 |
Gart | Naxd | ENSRNOP00000033253 | ENSRNOP00000060397 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.654 |
Gart | Naxe | ENSRNOP00000033253 | ENSRNOP00000025986 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.589 |
Mrpl28 | Mrps23 | ENSRNOP00000027662 | ENSRNOP00000013771 | Similar to 39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28). | Mitochondrial ribosomal protein S23 (Predicted), isoform CRA_b. | 0.937 |
Mrpl28 | Naxd | ENSRNOP00000027662 | ENSRNOP00000060397 | Similar to 39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28). | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.571 |
Mrpl28 | Naxe | ENSRNOP00000027662 | ENSRNOP00000025986 | Similar to 39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28). | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.736 |
Mrpl28 | Nudt14 | ENSRNOP00000027662 | ENSRNOP00000019550 | Similar to 39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28). | Nudix (Nucleoside diphosphate linked moiety X)-type motif 14 (Predicted). | 0.582 |
Mrpl28 | Tmem160 | ENSRNOP00000027662 | ENSRNOP00000020609 | Similar to 39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28). | Transmembrane protein 160. | 0.640 |
Mrps23 | Mrpl28 | ENSRNOP00000013771 | ENSRNOP00000027662 | Mitochondrial ribosomal protein S23 (Predicted), isoform CRA_b. | Similar to 39S ribosomal protein L28, mitochondrial (L28mt) (MRP-L28). | 0.937 |
Mrps23 | Naxd | ENSRNOP00000013771 | ENSRNOP00000060397 | Mitochondrial ribosomal protein S23 (Predicted), isoform CRA_b. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.588 |
Mrps23 | Naxe | ENSRNOP00000013771 | ENSRNOP00000025986 | Mitochondrial ribosomal protein S23 (Predicted), isoform CRA_b. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.714 |
Mrps23 | Nudt14 | ENSRNOP00000013771 | ENSRNOP00000019550 | Mitochondrial ribosomal protein S23 (Predicted), isoform CRA_b. | Nudix (Nucleoside diphosphate linked moiety X)-type motif 14 (Predicted). | 0.610 |
Mrps23 | Tmem160 | ENSRNOP00000013771 | ENSRNOP00000020609 | Mitochondrial ribosomal protein S23 (Predicted), isoform CRA_b. | Transmembrane protein 160. | 0.570 |
Naxd | Echdc1 | ENSRNOP00000060397 | ENSRNOP00000015440 | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | Ethylmalonyl-CoA decarboxylase; Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading. Also has methylmalonyl-CoA decarboxylase activity at lower level; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.647 |