STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lratd1LRAT domain-containing 1. (320 aa)    
Predicted Functional Partners:
Ankrd55
Ankyrin repeat domain 55.
      
 0.713
Dact2
Dishevelled-binding antagonist of beta-catenin 2.
   
    0.615
Fam49a
Family with sequence similarity 49, member A.
      
 0.601
Nt5dc2
5'-nucleotidase domain-containing protein 2.
      
 0.596
Ppp1r1a
Protein phosphatase 1 regulatory subunit 1A; Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
   
  
 0.594
Stk32a
Serine/threonine kinase 32A; Belongs to the protein kinase superfamily.
      
 0.582
Dop1a
DOP1 leucine zipper-like protein A.
      
 0.574
Rnf113a1
RING finger protein 113A-like.
   
  
 0.574
Rnf113a
Ring finger protein 113A1.
      
 0.565
Plaat1
HRAS-like suppressor (Predicted), isoform CRA_b.
      
 0.563
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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