STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Smim7Small integral membrane protein 7. (75 aa)    
Predicted Functional Partners:
Cog2
Component of oligomeric golgi complex 2.
   
 
 0.882
Cog8
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
   
 
 0.875
Cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 
 0.867
Cog3
Component of oligomeric golgi complex 3.
    
 
 0.865
Cog1
Component of oligomeric golgi complex 1.
   
 
 0.832
Cog5
Component of oligomeric golgi complex 5.
    
 
 0.831
Cog7
Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.
   
 
 0.729
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis) (Predicted), isoform CRA_a.
    
 
 0.679
Scfd1
Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi.
   
 
 0.648
Tmem38a
Trimeric intracellular cation channel type A; Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
   
  
 0.520
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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