node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bet1 | Bet1l | ENSRNOP00000014810 | ENSRNOP00000017684 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | 0.910 |
Bet1 | Gosr1 | ENSRNOP00000014810 | ENSRNOP00000068434 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an import [...] | 0.999 |
Bet1 | Gosr2 | ENSRNOP00000014810 | ENSRNOP00000005046 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.999 |
Bet1 | Scfd1 | ENSRNOP00000014810 | ENSRNOP00000039132 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi. | 0.999 |
Bet1 | Sec22a | ENSRNOP00000014810 | ENSRNOP00000061258 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Vesicle-trafficking protein SEC22a; May be involved in vesicle transport between the ER and the Golgi complex. | 0.968 |
Bet1 | Sec23a | ENSRNOP00000014810 | ENSRNOP00000006369 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.788 |
Bet1 | Stx5 | ENSRNOP00000014810 | ENSRNOP00000025664 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. | 0.999 |
Bet1 | Stx6 | ENSRNOP00000014810 | ENSRNOP00000037536 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Syntaxin-6; Involved in intracellular vesicle trafficking. | 0.935 |
Bet1 | Vti1a | ENSRNOP00000014810 | ENSRNOP00000058953 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2 (By similarity). May be concerned with increased secretion of cytokines as [...] | 0.991 |
Bet1 | Ykt6 | ENSRNOP00000014810 | ENSRNOP00000020693 | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.998 |
Bet1l | Bet1 | ENSRNOP00000017684 | ENSRNOP00000014810 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | BET1 homolog; Required for vesicular transport from the ER to the Golgi complex. Functions as a SNARE involved in the docking process of ER- derived vesicles with the cis-Golgi membrane. | 0.910 |
Bet1l | Gosr1 | ENSRNOP00000017684 | ENSRNOP00000068434 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an import [...] | 0.999 |
Bet1l | Gosr2 | ENSRNOP00000017684 | ENSRNOP00000005046 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.998 |
Bet1l | Scfd1 | ENSRNOP00000017684 | ENSRNOP00000039132 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi. | 0.927 |
Bet1l | Sec22a | ENSRNOP00000017684 | ENSRNOP00000061258 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Vesicle-trafficking protein SEC22a; May be involved in vesicle transport between the ER and the Golgi complex. | 0.849 |
Bet1l | Sec23a | ENSRNOP00000017684 | ENSRNOP00000006369 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.459 |
Bet1l | Stx5 | ENSRNOP00000017684 | ENSRNOP00000025664 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Syntaxin-5; Mediates endoplasmic reticulum to Golgi transport. Together with p115/USO1 and GM130/GOLGA2, involved in vesicle tethering and fusion at the cis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. | 0.999 |
Bet1l | Stx6 | ENSRNOP00000017684 | ENSRNOP00000037536 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Syntaxin-6; Involved in intracellular vesicle trafficking. | 0.847 |
Bet1l | Vti1a | ENSRNOP00000017684 | ENSRNOP00000058953 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Vesicle transport through interaction with t-SNAREs homolog 1A; V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2 (By similarity). May be concerned with increased secretion of cytokines as [...] | 0.920 |
Bet1l | Ykt6 | ENSRNOP00000017684 | ENSRNOP00000020693 | BET1-like protein; Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex. | Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity; Belongs to the synaptobrevin family. | 0.999 |