STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ovol2Zinc finger protein 339 (Predicted), isoform CRA_b. (241 aa)    
Predicted Functional Partners:
Grhl2
Grainyhead-like transcription factor 2.
   
  
 0.697
mrpl24
39S ribosomal protein L24, mitochondrial; Belongs to the universal ribosomal protein uL24 family.
      
 0.552
Gcm1
Chorion-specific transcription factor GCMa; Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development.
      
 0.499
Dzank1
Double zinc ribbon and ankyrin repeat domains 1.
      
 0.469
Esrp1
Epithelial splicing regulatory protein 1; mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity). Regulates splicing and exp [...]
   
  
 0.468
Itpripl1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1.
      
 0.467
Wdr54
Similar to D3Mm3e (Predicted), isoform CRA_a.
      
 0.453
Ervfrd-1
Endogenous retrovirus group FRD member 1, envelope.
   
 
 0.453
Wdr54-2
WD repeat-containing protein 54.
      
 0.453
Grhl3
Transcription factor CP2-like 4 (Predicted).
   
  
 0.452
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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