node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Eif6 | LOC103689968 | ENSRNOP00000071658 | ENSRNOP00000073087 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | 0.932 |
Eif6 | Lsg1 | ENSRNOP00000071658 | ENSRNOP00000074962 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Large subunit GTPase 1 homolog; GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity). | 0.972 |
Eif6 | Mak16 | ENSRNOP00000071658 | ENSRNOP00000015297 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Protein MAK16 homolog; Belongs to the MAK16 family. | 0.901 |
Eif6 | Mrto4 | ENSRNOP00000071658 | ENSRNOP00000024326 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.989 |
Eif6 | Nmd3 | ENSRNOP00000071658 | ENSRNOP00000063236 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.978 |
Eif6 | Nsa2 | ENSRNOP00000071658 | ENSRNOP00000022138 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Ribosome biogenesis protein NSA2 homolog; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity). | 0.953 |
Eif6 | Rpf1 | ENSRNOP00000071658 | ENSRNOP00000021705 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Ribosome production factor 1; May be required for ribosome biogenesis. | 0.976 |
Eif6 | Rpl23 | ENSRNOP00000071658 | ENSRNOP00000005471 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 0.983 |
Eif6 | Rsl24d1 | ENSRNOP00000071658 | ENSRNOP00000068858 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity). | 0.976 |
Eif6 | Wdr12 | ENSRNOP00000071658 | ENSRNOP00000023463 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.988 |
LOC103689968 | Eif6 | ENSRNOP00000073087 | ENSRNOP00000071658 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] | 0.932 |
LOC103689968 | Lsg1 | ENSRNOP00000073087 | ENSRNOP00000074962 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | Large subunit GTPase 1 homolog; GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity). | 0.854 |
LOC103689968 | Mak16 | ENSRNOP00000073087 | ENSRNOP00000015297 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | Protein MAK16 homolog; Belongs to the MAK16 family. | 0.744 |
LOC103689968 | Mrto4 | ENSRNOP00000073087 | ENSRNOP00000024326 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.820 |
LOC103689968 | Nmd3 | ENSRNOP00000073087 | ENSRNOP00000063236 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.874 |
LOC103689968 | Nsa2 | ENSRNOP00000073087 | ENSRNOP00000022138 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | Ribosome biogenesis protein NSA2 homolog; Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity). | 0.735 |
LOC103689968 | Rpf1 | ENSRNOP00000073087 | ENSRNOP00000021705 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | Ribosome production factor 1; May be required for ribosome biogenesis. | 0.747 |
LOC103689968 | Rpl23 | ENSRNOP00000073087 | ENSRNOP00000005471 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | 60S ribosomal protein L23; Belongs to the universal ribosomal protein uL14 family. | 0.799 |
LOC103689968 | Rsl24d1 | ENSRNOP00000073087 | ENSRNOP00000068858 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | Probable ribosome biogenesis protein RLP24; Involved in the biogenesis of the 60S ribosomal subunit. Ensures the docking of GTPBP4/NOG1 to pre-60S particles (By similarity). | 0.745 |
LOC103689968 | Wdr12 | ENSRNOP00000073087 | ENSRNOP00000023463 | Zinc finger protein 622; May behave as an activator of the bound transcription factor, MYBL2, and be involved in embryonic development. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.722 |