node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC100362565 | Otop1 | ENSRNOP00000073135 | ENSRNOP00000047534 | Polycystin 1-like 3, transient receptor potential channel-interacting. | Proton channel OTOP1; Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates [...] | 0.526 |
LOC100362565 | Pkd1l1 | ENSRNOP00000073135 | ENSRNOP00000006498 | Polycystin 1-like 3, transient receptor potential channel-interacting. | Polycystin 1-like 1, transient receptor potential channel-interacting. | 0.454 |
LOC100362565 | Pkd1l2 | ENSRNOP00000073135 | ENSRNOP00000064630 | Polycystin 1-like 3, transient receptor potential channel-interacting. | Polycystic kidney disease 1 like 2. | 0.782 |
LOC100362565 | Pkd2l1 | ENSRNOP00000073135 | ENSRNOP00000062794 | Polycystin 1-like 3, transient receptor potential channel-interacting. | Polycystin 2-like 1, transient receptor potential cation channel. | 0.999 |
LOC100362565 | Plcb2 | ENSRNOP00000073135 | ENSRNOP00000070903 | Polycystin 1-like 3, transient receptor potential channel-interacting. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This protein may be involved in the transduction of bitter taste stimuli. | 0.574 |
LOC100362565 | Tas1r1 | ENSRNOP00000073135 | ENSRNOP00000013385 | Polycystin 1-like 3, transient receptor potential channel-interacting. | Taste receptor type 1 member 1; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. | 0.648 |
LOC100362565 | Tas1r3 | ENSRNOP00000073135 | ENSRNOP00000026671 | Polycystin 1-like 3, transient receptor potential channel-interacting. | Taste receptor type 1 member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses (By similarity). | 0.640 |
LOC100362565 | Tas2r139 | ENSRNOP00000073135 | ENSRNOP00000035471 | Polycystin 1-like 3, transient receptor potential channel-interacting. | Taste receptor type 2 member 39; Putative taste receptor which may play a role in the perception of bitterness. | 0.516 |
LOC100362565 | Trpm5 | ENSRNOP00000073135 | ENSRNOP00000039981 | Polycystin 1-like 3, transient receptor potential channel-interacting. | Transient receptor potential cation channel, subfamily M, member 5. | 0.762 |
Otop1 | LOC100362565 | ENSRNOP00000047534 | ENSRNOP00000073135 | Proton channel OTOP1; Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates [...] | Polycystin 1-like 3, transient receptor potential channel-interacting. | 0.526 |
Otop1 | Pkd2l1 | ENSRNOP00000047534 | ENSRNOP00000062794 | Proton channel OTOP1; Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates [...] | Polycystin 2-like 1, transient receptor potential cation channel. | 0.663 |
Otop1 | Plcb2 | ENSRNOP00000047534 | ENSRNOP00000070903 | Proton channel OTOP1; Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates [...] | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This protein may be involved in the transduction of bitter taste stimuli. | 0.687 |
Otop1 | Tas1r1 | ENSRNOP00000047534 | ENSRNOP00000013385 | Proton channel OTOP1; Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates [...] | Taste receptor type 1 member 1; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. | 0.568 |
Otop1 | Tas1r3 | ENSRNOP00000047534 | ENSRNOP00000026671 | Proton channel OTOP1; Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates [...] | Taste receptor type 1 member 3; Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate) and also to most of the 20 standard L-amino acids, but not to their D-enantiomers or other compounds. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses (By similarity). | 0.569 |
Otop1 | Trpm5 | ENSRNOP00000047534 | ENSRNOP00000039981 | Proton channel OTOP1; Proton-selective channel that specifically transports protons into cells. Proton channel activity is only weakly-sensitive to voltage. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. In the vestibular system of the inner ear, required for the formation and function of otoconia, which are calcium carbonate crystals that sense gravity and acceleration. Probably acts by maintaining the pH appropriate for formation of otoconia. Regulates [...] | Transient receptor potential cation channel, subfamily M, member 5. | 0.479 |
Pkd1 | Pkd2l1 | ENSRNOP00000015092 | ENSRNOP00000062794 | Polycystin 1, transient receptor potential channel-interacting. | Polycystin 2-like 1, transient receptor potential cation channel. | 0.794 |
Pkd1l1 | LOC100362565 | ENSRNOP00000006498 | ENSRNOP00000073135 | Polycystin 1-like 1, transient receptor potential channel-interacting. | Polycystin 1-like 3, transient receptor potential channel-interacting. | 0.454 |
Pkd1l1 | Pkd1l2 | ENSRNOP00000006498 | ENSRNOP00000064630 | Polycystin 1-like 1, transient receptor potential channel-interacting. | Polycystic kidney disease 1 like 2. | 0.452 |
Pkd1l1 | Pkd2l1 | ENSRNOP00000006498 | ENSRNOP00000062794 | Polycystin 1-like 1, transient receptor potential channel-interacting. | Polycystin 2-like 1, transient receptor potential cation channel. | 0.942 |
Pkd1l2 | LOC100362565 | ENSRNOP00000064630 | ENSRNOP00000073135 | Polycystic kidney disease 1 like 2. | Polycystin 1-like 3, transient receptor potential channel-interacting. | 0.782 |