node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hras | Kras | ENSRNOP00000022363 | ENSRNOP00000012588 | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. | GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity). | 0.756 |
Hras | Nras | ENSRNOP00000022363 | ENSRNOP00000036381 | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.902 |
Hras | Rgl1 | ENSRNOP00000022363 | ENSRNOP00000069394 | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. | Ral guanine nucleotide dissociation stimulator,-like 1. | 0.951 |
Hras | Rras | ENSRNOP00000022363 | ENSRNOP00000027809 | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. | Ras-related protein R-Ras; Regulates the organization of the actin cytoskeleton. With OSPBL3, modulates integrin beta-1 (ITGB1) activity. Belongs to the small GTPase superfamily. Ras family. | 0.906 |
Kiaa1107 | LOC689396 | ENSRNOP00000038747 | ENSRNOP00000049916 | AP2-interacting clathrin-endocytosis protein; Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission. | Similar to RNA polymerase II elongation factor ELL2. | 0.694 |
Kiaa1107 | Rgl1 | ENSRNOP00000038747 | ENSRNOP00000069394 | AP2-interacting clathrin-endocytosis protein; Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission. | Ral guanine nucleotide dissociation stimulator,-like 1. | 0.561 |
Kras | Hras | ENSRNOP00000012588 | ENSRNOP00000022363 | GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity). | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. | 0.756 |
Kras | Nras | ENSRNOP00000012588 | ENSRNOP00000036381 | GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity). | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.524 |
Kras | Rgl1 | ENSRNOP00000012588 | ENSRNOP00000069394 | GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity). | Ral guanine nucleotide dissociation stimulator,-like 1. | 0.762 |
LOC689396 | Kiaa1107 | ENSRNOP00000049916 | ENSRNOP00000038747 | Similar to RNA polymerase II elongation factor ELL2. | AP2-interacting clathrin-endocytosis protein; Involved in clathrin-mediated endocytosis at the synapse. Plays a role in neuronal development and in synaptic vesicle recycling in mature neurons, a process required for normal synaptic transmission. | 0.694 |
LOC689396 | Rgl1 | ENSRNOP00000049916 | ENSRNOP00000069394 | Similar to RNA polymerase II elongation factor ELL2. | Ral guanine nucleotide dissociation stimulator,-like 1. | 0.711 |
Mras | Rgl1 | ENSRNOP00000045851 | ENSRNOP00000069394 | Ras-related protein M-Ras; Serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Activates the MAP kinase pathway (By similarity); Belongs to the small GTPase superfamily. Ras family. | Ral guanine nucleotide dissociation stimulator,-like 1. | 0.937 |
Mras | Rras2 | ENSRNOP00000045851 | ENSRNOP00000017199 | Ras-related protein M-Ras; Serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Activates the MAP kinase pathway (By similarity); Belongs to the small GTPase superfamily. Ras family. | Related RAS viral (R-ras) oncogene homolog 2. | 0.408 |
Nras | Hras | ENSRNOP00000036381 | ENSRNOP00000022363 | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. | 0.902 |
Nras | Kras | ENSRNOP00000036381 | ENSRNOP00000012588 | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity). | 0.524 |
Nras | Rgl1 | ENSRNOP00000036381 | ENSRNOP00000069394 | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | Ral guanine nucleotide dissociation stimulator,-like 1. | 0.964 |
Nras | Rras | ENSRNOP00000036381 | ENSRNOP00000027809 | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | Ras-related protein R-Ras; Regulates the organization of the actin cytoskeleton. With OSPBL3, modulates integrin beta-1 (ITGB1) activity. Belongs to the small GTPase superfamily. Ras family. | 0.909 |
Rala | Ralb | ENSRNOP00000018190 | ENSRNOP00000003413 | Ras-related protein Ral-A; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells (By similarity). Th [...] | Ras-related protein Ral-B; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Required for suppression of apoptosis (By similarity). In late stages of cy [...] | 0.925 |
Rala | Rgl1 | ENSRNOP00000018190 | ENSRNOP00000069394 | Ras-related protein Ral-A; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells (By similarity). Th [...] | Ral guanine nucleotide dissociation stimulator,-like 1. | 0.965 |
Ralb | Rala | ENSRNOP00000003413 | ENSRNOP00000018190 | Ras-related protein Ral-B; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Required for suppression of apoptosis (By similarity). In late stages of cy [...] | Ras-related protein Ral-A; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells (By similarity). Th [...] | 0.925 |