node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arhgap31 | Cdc42 | ENSRNOP00000004138 | ENSRNOP00000030928 | Cdc42 GTPase-activating protein (Predicted). | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | 0.763 |
Arhgap31 | Dock6 | ENSRNOP00000004138 | ENSRNOP00000075398 | Cdc42 GTPase-activating protein (Predicted). | Dedicator of cytokinesis 6; Belongs to the DOCK family. | 0.641 |
Arhgap31 | Eogt | ENSRNOP00000004138 | ENSRNOP00000073147 | Cdc42 GTPase-activating protein (Predicted). | EGF domain-specific O-linked N-acetylglucosamine transferase; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains. Belongs to the glycosyltransferase 61 family. | 0.548 |
Arhgap31 | Rac1 | ENSRNOP00000004138 | ENSRNOP00000001417 | Cdc42 GTPase-activating protein (Predicted). | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.492 |
Cdc42 | Arhgap31 | ENSRNOP00000030928 | ENSRNOP00000004138 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Cdc42 GTPase-activating protein (Predicted). | 0.763 |
Cdc42 | Dock2 | ENSRNOP00000030928 | ENSRNOP00000056557 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Uncharacterized protein; Belongs to the DOCK family. | 0.688 |
Cdc42 | Dock5 | ENSRNOP00000030928 | ENSRNOP00000055674 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Dedicator of cytokinesis 5; Belongs to the DOCK family. | 0.788 |
Cdc42 | Dock6 | ENSRNOP00000030928 | ENSRNOP00000075398 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Dedicator of cytokinesis 6; Belongs to the DOCK family. | 0.884 |
Cdc42 | Dock8 | ENSRNOP00000030928 | ENSRNOP00000015668 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Dedicator of cytokinesis 8; Belongs to the DOCK family. | 0.998 |
Cdc42 | Rac1 | ENSRNOP00000030928 | ENSRNOP00000001417 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.954 |
Cdc42 | Rhog | ENSRNOP00000030928 | ENSRNOP00000027641 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | Ras homolog gene family, member G (Rho G). | 0.565 |
Dock2 | Cdc42 | ENSRNOP00000056557 | ENSRNOP00000030928 | Uncharacterized protein; Belongs to the DOCK family. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | 0.688 |
Dock2 | Dock6 | ENSRNOP00000056557 | ENSRNOP00000075398 | Uncharacterized protein; Belongs to the DOCK family. | Dedicator of cytokinesis 6; Belongs to the DOCK family. | 0.726 |
Dock2 | Dock8 | ENSRNOP00000056557 | ENSRNOP00000015668 | Uncharacterized protein; Belongs to the DOCK family. | Dedicator of cytokinesis 8; Belongs to the DOCK family. | 0.565 |
Dock2 | Rac1 | ENSRNOP00000056557 | ENSRNOP00000001417 | Uncharacterized protein; Belongs to the DOCK family. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.962 |
Dock2 | Rhog | ENSRNOP00000056557 | ENSRNOP00000027641 | Uncharacterized protein; Belongs to the DOCK family. | Ras homolog gene family, member G (Rho G). | 0.599 |
Dock5 | Cdc42 | ENSRNOP00000055674 | ENSRNOP00000030928 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase (By similarity). Regulates cell migration (By similarity). In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface proj [...] | 0.788 |
Dock5 | Dock6 | ENSRNOP00000055674 | ENSRNOP00000075398 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Dedicator of cytokinesis 6; Belongs to the DOCK family. | 0.573 |
Dock5 | Dock8 | ENSRNOP00000055674 | ENSRNOP00000015668 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Dedicator of cytokinesis 8; Belongs to the DOCK family. | 0.552 |
Dock5 | Rac1 | ENSRNOP00000055674 | ENSRNOP00000001417 | Dedicator of cytokinesis 5; Belongs to the DOCK family. | Ras-related C3 botulinum toxin substrate 1; Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity [...] | 0.788 |