STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Accsl1-aminocyclopropane-1-carboxylate synthase-like. (617 aa)    
Predicted Functional Partners:
Flcn
Folliculin; May be a tumor suppressor. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1 (By similarity). Belongs to the folliculin family.
    
   0.702
Dmrtc2
Doublesex- and mab-3-related transcription factor C2-like.
    
 
 0.681
LOC100910371
DMRT-like family C2.
    
 
 0.681
Patl2
PAT1 homolog 2.
   
  
 0.676
Ifne
Interferon, epsilon.
      
 0.641
Btg4
BTG anti-proliferation factor 4.
      
 0.620
St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, isoform CRA_a; Belongs to the glycosyltransferase 29 family.
   
  
 0.615
Wee2
Wee1-like protein kinase.
      
 0.600
Aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
  
 0.572
Aldh18a1-2
Aldehyde dehydrogenase 18 family, member A1.
  
  
 0.572
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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