node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Armc9 | Drc7 | ENSRNOP00000059344 | ENSRNOP00000032646 | LisH domain-containing protein ARMC9; Acts as a positive regulator of hedgehog (Hh) signaling (By similarity). Involved in ciliogenesis (By similarity). May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (By similarity). | Dynein regulatory complex subunit 7. | 0.444 |
Armc9 | Ttll10 | ENSRNOP00000059344 | ENSRNOP00000070186 | LisH domain-containing protein ARMC9; Acts as a positive regulator of hedgehog (Hh) signaling (By similarity). Involved in ciliogenesis (By similarity). May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (By similarity). | Protein polyglycylase TTLL10; Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Polyglycylates alpha-tubulin and beta-tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin. Has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase (By similarity). | 0.471 |
Ccnl2 | Ttll10 | ENSRNOP00000025531 | ENSRNOP00000070186 | Cyclin-L2; Involved in pre-mRNA splicing. May induce cell death, possibly by acting on the transcription and RNA processing of apoptosis-related factors. | Protein polyglycylase TTLL10; Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Polyglycylates alpha-tubulin and beta-tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin. Has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase (By similarity). | 0.517 |
Dnali1 | Drc7 | ENSRNOP00000032193 | ENSRNOP00000032646 | Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family. | Dynein regulatory complex subunit 7. | 0.520 |
Dnali1 | Ift52 | ENSRNOP00000032193 | ENSRNOP00000059169 | Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family. | Intraflagellar transport 52. | 0.660 |
Dnali1 | Tmem17 | ENSRNOP00000032193 | ENSRNOP00000012224 | Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family. | Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). | 0.468 |
Dnali1 | Ttc25 | ENSRNOP00000032193 | ENSRNOP00000075373 | Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family. | Tetratricopeptide repeat domain 25. | 0.708 |
Dnali1 | Ttll10 | ENSRNOP00000032193 | ENSRNOP00000070186 | Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family. | Protein polyglycylase TTLL10; Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Polyglycylates alpha-tubulin and beta-tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin. Has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase (By similarity). | 0.497 |
Drc7 | Armc9 | ENSRNOP00000032646 | ENSRNOP00000059344 | Dynein regulatory complex subunit 7. | LisH domain-containing protein ARMC9; Acts as a positive regulator of hedgehog (Hh) signaling (By similarity). Involved in ciliogenesis (By similarity). May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (By similarity). | 0.444 |
Drc7 | Dnali1 | ENSRNOP00000032646 | ENSRNOP00000032193 | Dynein regulatory complex subunit 7. | Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family. | 0.520 |
Drc7 | Ift52 | ENSRNOP00000032646 | ENSRNOP00000059169 | Dynein regulatory complex subunit 7. | Intraflagellar transport 52. | 0.467 |
Drc7 | Tmem17 | ENSRNOP00000032646 | ENSRNOP00000012224 | Dynein regulatory complex subunit 7. | Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). | 0.485 |
Drc7 | Ttc25 | ENSRNOP00000032646 | ENSRNOP00000075373 | Dynein regulatory complex subunit 7. | Tetratricopeptide repeat domain 25. | 0.527 |
Drc7 | Ttll10 | ENSRNOP00000032646 | ENSRNOP00000070186 | Dynein regulatory complex subunit 7. | Protein polyglycylase TTLL10; Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Polyglycylates alpha-tubulin and beta-tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin. Has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase (By similarity). | 0.566 |
Ift52 | Dnali1 | ENSRNOP00000059169 | ENSRNOP00000032193 | Intraflagellar transport 52. | Axonemal dynein light intermediate polypeptide 1; May play a dynamic role in flagellar motility; Belongs to the inner dynein arm light chain family. | 0.660 |
Ift52 | Drc7 | ENSRNOP00000059169 | ENSRNOP00000032646 | Intraflagellar transport 52. | Dynein regulatory complex subunit 7. | 0.467 |
Ift52 | Tmem17 | ENSRNOP00000059169 | ENSRNOP00000012224 | Intraflagellar transport 52. | Transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). | 0.498 |
Ift52 | Ttc25 | ENSRNOP00000059169 | ENSRNOP00000075373 | Intraflagellar transport 52. | Tetratricopeptide repeat domain 25. | 0.474 |
Ift52 | Ttll10 | ENSRNOP00000059169 | ENSRNOP00000070186 | Intraflagellar transport 52. | Protein polyglycylase TTLL10; Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Polyglycylates alpha-tubulin and beta-tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin. Has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase (By similarity). | 0.479 |
Mxra8 | Ttll10 | ENSRNOP00000075625 | ENSRNOP00000070186 | Matrix remodeling-associated protein 8; Transmembrane protein which can modulate activity of various signaling pathways, probably via binding to integrin ITGAV:ITGB3. Mediates heterophilic cell-cell interactions in vitro. Inhibits osteoclastogenesis downstream of TNFSF11/RANKL and CSF1, where it may function by attenuating signaling via integrin ITGB3 and MAP kinase p38. Plays a role in cartilage formation where it promotes proliferation and maturation of growth plate chondrocytes. Stimulates formation of primary cilia in chondrocytes. Enhances expression of genes involved in the hedge [...] | Protein polyglycylase TTLL10; Polyglycylase which modifies both tubulin and non-tubulin proteins, generating side chains of glycine on the gamma-carboxyl groups of specific glutamate residues of target proteins. Polyglycylates alpha-tubulin and beta-tubulin, but is not able to initiate glycylation and only has activity toward monoglycylated tubulin. Has the ability to polyglycylate non-tubulin proteins such as NAP1; in this case it can initiate glycylation and does not require preliminary monoglycylation by another glycylase (By similarity). | 0.571 |