STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srek1ip1Protein SREK1IP1; Possible splicing regulator involved in the control of cellular survival. (153 aa)    
Predicted Functional Partners:
Srek1
Splicing regulatory glutamine/lysine-rich protein 1; Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3.
      
 0.789
Creg2
Cellular repressor of E1A-stimulated genes 2; Belongs to the CREG family.
      
 0.745
Znf761
Zinc finger protein 51.
      
 0.726
Rnf180
Ring finger protein 180.
      
 0.697
Ppwd1
Peptidylprolyl isomerase domain and WD repeat containing 1 (Predicted).
   
  
 0.695
Shisal2b
Shisa-like 2B.
      
 0.690
Lemd3
LEM domain-containing 3.
      
 0.674
Sfxn3
Sideroflexin-3; Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway. Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors. Belongs to the sideroflexin family.
      
 0.638
Ccdc61
Coiled-coil domain-containing protein 61.
      
 0.637
Zfat
Zinc finger and AT hook domain-containing.
   
  
 0.607
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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