STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Zfp82Zinc finger protein 82. (501 aa)    
Predicted Functional Partners:
Fibcd1
Fibrinogen C domain containing 1-like 1.
    
 
 0.678
Fibcd1l1
Fibrinogen C domain containing 1 (Predicted).
    
 
 0.677
Gpr149
Probable G-protein coupled receptor 149; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.647
Lingo2
Ig-like domain-containing protein.
    
 
 0.628
Hecw1
Similar to HECT type E3 ubiquitin ligase (Predicted), isoform CRA_b.
    
 
 0.599
Ajap1
Adherens junction-associated protein 1; Plays a role in cell adhesion and cell migration.
      
 0.571
Eif2s3y
Eukaryotic translation initiation factor 2 subunit 3, Y-linked; As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary com [...]
      
 0.489
Kdm5d
Lysine demethylase 5D.
    
 
 0.485
Ddx3y
DEAD-box helicase 3, Y-linked; Belongs to the DEAD box helicase family.
   
 
 0.476
Ddx3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3; Belongs to the DEAD box helicase family.
   
 
 0.440
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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