STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lyrm7Complex III assembly factor LYRM7; Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane (By similarity). (104 aa)    
Predicted Functional Partners:
Uqcrfs1
Cytochrome b-c1 complex subunit Rieske, mitochondrial; [Cytochrome b-c1 complex subunit Rieske, mitochondrial]: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b- c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and su [...]
    
 
 0.853
Mrpl3
39S ribosomal protein L3, mitochondrial; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.812
Mrpl4
Mitochondrial ribosomal protein L4 (Predicted), isoform CRA_b.
   
 
 0.799
Mrpl19
Ribosomal protein, mitochondrial, L15.
   
 
 0.797
Mrpl27
Mitochondrial ribosomal protein L27 (Predicted), isoform CRA_a.
   
 
 0.791
Mrpl46
39S ribosomal protein L46, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL46 family.
   
 
 0.786
Mrpl40
39S ribosomal protein L40, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL40 family.
   
 
 0.785
Ubxn7
UBX domain-containing protein 7.
    
   0.780
LOC100911374
UBX domain-containing protein 7-like.
    
   0.780
Mrpl33
Brain and reproductive organ-expressed protein, isoform CRA_c.
   
 
 0.779
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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