STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hmgb3-2Similar to High mobility group protein 4 (HMG-4) (High mobility group protein 2a) (HMG-2a). (200 aa)    
Predicted Functional Partners:
Olr278
Olfactory receptor.
      
 0.489
Polr3f
DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
   
 
 0.448
Yipf6
Protein YIPF6; May be required for stable YIPF1 and YIPF2 protein expression.
    
 
 0.445
Mmd
Monocyte to macrophage differentiation factor; Is involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion.
      
 0.445
Smarca1
SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 1.
   
 
 0.419
Wdfy1
WD repeat and FYVE domain-containing 1.
   
 
 0.416
Frmd7
FERM domain-containing 7.
      
 0.405
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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