STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Enox1Ecto-NOX disulfide-thiol exchanger 1. (643 aa)    
Predicted Functional Partners:
Ctif
Cap-binding complex-dependent translation initiation factor.
      
 0.636
Retreg3
Reticulophagy regulator family member 3.
      
 0.619
Clec2e
C-type lectin domain family 2 member d10.
      
 0.535
Dleu7
Deleted in lymphocytic leukemia, 7 (Predicted), isoform CRA_b.
      
 0.503
Trappc3
Trafficking protein particle complex subunit 3; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
      
 0.500
Ankrd10
Ankyrin repeat domain 10.
      
 0.489
Tom1l1
TOM1-like protein 1; Probable adapter protein involved in signaling pathways. Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated. May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity). Belongs to the TOM1 family.
      
 0.477
Gtf2f2
General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity (By similarity).
      
 0.475
RGD1564899
Cardiac-enriched FHL2-interacting protein; Plays an important role in cardiomyocyte hypertrophy via activation of the calcineurin/NFAT signaling pathway.
      
 0.469
Lrrn2
Leucine-rich repeat neuronal 2.
   
  
 0.462
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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