node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Becn1 | Cisd2 | ENSRNOP00000071966 | ENSRNOP00000066613 | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | Similar to RIKEN cDNA 1500009M05 (Predicted). | 0.582 |
Cisd2 | Becn1 | ENSRNOP00000066613 | ENSRNOP00000071966 | Similar to RIKEN cDNA 1500009M05 (Predicted). | Beclin-1-C 35 kDa; Plays a central role in autophagy. Acts as core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3- phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2. Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex f [...] | 0.582 |
Cisd2 | F1LTU8_RAT | ENSRNOP00000066613 | ENSRNOP00000000351 | Similar to RIKEN cDNA 1500009M05 (Predicted). | zf-Tim10_DDP domain-containing protein. | 0.641 |
Cisd2 | ND4 | ENSRNOP00000066613 | ENSRNOP00000043141 | Similar to RIKEN cDNA 1500009M05 (Predicted). | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | 0.573 |
Cisd2 | Ndufa8 | ENSRNOP00000066613 | ENSRNOP00000050148 | Similar to RIKEN cDNA 1500009M05 (Predicted). | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.710 |
Cisd2 | Ndufb7 | ENSRNOP00000066613 | ENSRNOP00000034511 | Similar to RIKEN cDNA 1500009M05 (Predicted). | NADH dehydrogenase (Ubiquinone) 1 beta subcomplex, 7 (Predicted). | 0.585 |
Cisd2 | Sdhd | ENSRNOP00000066613 | ENSRNOP00000055942 | Similar to RIKEN cDNA 1500009M05 (Predicted). | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. | 0.671 |
Cisd2 | Timm10 | ENSRNOP00000066613 | ENSRNOP00000010619 | Similar to RIKEN cDNA 1500009M05 (Predicted). | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. | 0.819 |
Cisd2 | Timm10b | ENSRNOP00000066613 | ENSRNOP00000064088 | Similar to RIKEN cDNA 1500009M05 (Predicted). | Mitochondrial import inner membrane translocase subunit Tim10 B; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. | 0.641 |
Cisd2 | Timm9 | ENSRNOP00000066613 | ENSRNOP00000010871 | Similar to RIKEN cDNA 1500009M05 (Predicted). | Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. | 0.649 |
Cisd2 | Wfs1 | ENSRNOP00000066613 | ENSRNOP00000032218 | Similar to RIKEN cDNA 1500009M05 (Predicted). | Wolframin ER transmembrane glycoprotein. | 0.767 |
F1LTU8_RAT | Cisd2 | ENSRNOP00000000351 | ENSRNOP00000066613 | zf-Tim10_DDP domain-containing protein. | Similar to RIKEN cDNA 1500009M05 (Predicted). | 0.641 |
F1LTU8_RAT | Sdhd | ENSRNOP00000000351 | ENSRNOP00000055942 | zf-Tim10_DDP domain-containing protein. | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. | 0.630 |
F1LTU8_RAT | Timm10 | ENSRNOP00000000351 | ENSRNOP00000010619 | zf-Tim10_DDP domain-containing protein. | Mitochondrial import inner membrane translocase subunit Tim10; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. | 0.968 |
F1LTU8_RAT | Timm10b | ENSRNOP00000000351 | ENSRNOP00000064088 | zf-Tim10_DDP domain-containing protein. | Mitochondrial import inner membrane translocase subunit Tim10 B; Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin-pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space. | 0.544 |
F1LTU8_RAT | Timm9 | ENSRNOP00000000351 | ENSRNOP00000010871 | zf-Tim10_DDP domain-containing protein. | Mitochondrial import inner membrane translocase subunit Tim9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity); Belongs to the small Tim family. | 0.872 |
ND4 | Cisd2 | ENSRNOP00000043141 | ENSRNOP00000066613 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | Similar to RIKEN cDNA 1500009M05 (Predicted). | 0.573 |
ND4 | Ndufa8 | ENSRNOP00000043141 | ENSRNOP00000050148 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.999 |
ND4 | Ndufb7 | ENSRNOP00000043141 | ENSRNOP00000034511 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | NADH dehydrogenase (Ubiquinone) 1 beta subcomplex, 7 (Predicted). | 0.999 |
ND4 | Sdhd | ENSRNOP00000043141 | ENSRNOP00000055942 | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. | 0.425 |