STRINGSTRING
Gsg2 protein (Rattus norvegicus) - STRING interaction network
"Gsg2" - Germ cell associated 2 in Rattus norvegicus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
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[Homology]
Score
Gsg2Germ cell associated 2 (haspin) (751 aa)    
Predicted Functional Partners:
Bub1
Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted); BUB1 mitotic checkpoint serine/threonine kinase (1059 aa)
     
   
  0.879
Incenp
Inner centromere protein (895 aa)
     
   
  0.832
Aurkb
Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] (343 aa)
     
 
  0.827
Sgol1
Shugoshin-like 1 (S. pombe) (522 aa)
     
 
  0.759
Cdca8
Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity) (223 aa)
     
   
  0.718
Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B (1052 aa)
     
   
  0.709
Plk1
Serine/threonine-protein kinase PLK1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CC [...] (603 aa)
     
   
  0.695
ENSRNOG00000045820
Histone H3 (136 aa)
     
 
  0.687
Hist1h3c
Histone cluster 2, H3c2 (136 aa)
     
 
  0.687
Hist1h3f
Histone cluster 1, H2ai-like1; Belongs to the histone H3 family (136 aa)
     
 
  0.683
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Gunn rats, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus norvegicus, Rattus rattiscus, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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