node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aurkb | Bub1 | ENSRNOP00000072371 | ENSRNOP00000042114 | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | 0.929 |
Aurkb | Cdca5 | ENSRNOP00000072371 | ENSRNOP00000064620 | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | Cell division cycle-associated 5. | 0.680 |
Aurkb | Cdca8 | ENSRNOP00000072371 | ENSRNOP00000043633 | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). | 0.996 |
Aurkb | Cenpa | ENSRNOP00000072371 | ENSRNOP00000012512 | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | Similar to centromere protein A (Predicted), isoform CRA_b. | 0.954 |
Aurkb | Haspin | ENSRNOP00000072371 | ENSRNOP00000067027 | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | Histone H3-associated protein kinase. | 0.631 |
Aurkb | Incenp | ENSRNOP00000072371 | ENSRNOP00000071544 | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | Inner centromere protein. | 0.998 |
Aurkb | Kif2c | ENSRNOP00000072371 | ENSRNOP00000025903 | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome- microtubule attachment. | 0.911 |
Aurkb | Sgo1 | ENSRNOP00000072371 | ENSRNOP00000061236 | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | Shugoshin 1. | 0.807 |
Bub1 | Aurkb | ENSRNOP00000042114 | ENSRNOP00000072371 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | 0.929 |
Bub1 | Cdca5 | ENSRNOP00000042114 | ENSRNOP00000064620 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Cell division cycle-associated 5. | 0.737 |
Bub1 | Cdca8 | ENSRNOP00000042114 | ENSRNOP00000043633 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). | 0.942 |
Bub1 | Cenpa | ENSRNOP00000042114 | ENSRNOP00000012512 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Similar to centromere protein A (Predicted), isoform CRA_b. | 0.933 |
Bub1 | Haspin | ENSRNOP00000042114 | ENSRNOP00000067027 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Histone H3-associated protein kinase. | 0.800 |
Bub1 | Incenp | ENSRNOP00000042114 | ENSRNOP00000071544 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Inner centromere protein. | 0.862 |
Bub1 | Kif2c | ENSRNOP00000042114 | ENSRNOP00000025903 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Kinesin-like protein KIF2C; In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome- microtubule attachment. | 0.966 |
Bub1 | Sgo1 | ENSRNOP00000042114 | ENSRNOP00000061236 | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | Shugoshin 1. | 0.944 |
Cdca5 | Aurkb | ENSRNOP00000064620 | ENSRNOP00000072371 | Cell division cycle-associated 5. | Aurora kinase B; Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of [...] | 0.680 |
Cdca5 | Bub1 | ENSRNOP00000064620 | ENSRNOP00000042114 | Cell division cycle-associated 5. | Budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae) (Predicted). | 0.737 |
Cdca5 | Cdca8 | ENSRNOP00000064620 | ENSRNOP00000043633 | Cell division cycle-associated 5. | Borealin; Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA (By similarity). | 0.942 |
Cdca5 | Cenpa | ENSRNOP00000064620 | ENSRNOP00000012512 | Cell division cycle-associated 5. | Similar to centromere protein A (Predicted), isoform CRA_b. | 0.411 |