node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cdhr5 | Hmgn1 | ENSRNOP00000044906 | ENSRNOP00000067432 | Cadherin-related family member 5; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. | Non-histone chromosomal protein HMG-14-like. | 0.437 |
H2az2 | Hmgb2 | ENSRNOP00000073832 | ENSRNOP00000017635 | Histone H2A; Belongs to the histone H2A family. | High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes (By similarity). Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor bindi [...] | 0.416 |
H2az2 | Hmgb2-2 | ENSRNOP00000073832 | ENSRNOP00000039358 | Histone H2A; Belongs to the histone H2A family. | High mobility group box 2-like 1. | 0.437 |
H2az2 | Hmgn1 | ENSRNOP00000073832 | ENSRNOP00000067432 | Histone H2A; Belongs to the histone H2A family. | Non-histone chromosomal protein HMG-14-like. | 0.417 |
Hmgb2 | H2az2 | ENSRNOP00000017635 | ENSRNOP00000073832 | High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes (By similarity). Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor bindi [...] | Histone H2A; Belongs to the histone H2A family. | 0.416 |
Hmgb2 | Hmgn1 | ENSRNOP00000017635 | ENSRNOP00000067432 | High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes (By similarity). Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor bindi [...] | Non-histone chromosomal protein HMG-14-like. | 0.590 |
Hmgb2 | Hmgn2 | ENSRNOP00000017635 | ENSRNOP00000074978 | High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes (By similarity). Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor bindi [...] | Non-histone chromosomal protein HMG-17; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity). | 0.560 |
Hmgb2-2 | H2az2 | ENSRNOP00000039358 | ENSRNOP00000073832 | High mobility group box 2-like 1. | Histone H2A; Belongs to the histone H2A family. | 0.437 |
Hmgb2-2 | Hmgn1 | ENSRNOP00000039358 | ENSRNOP00000067432 | High mobility group box 2-like 1. | Non-histone chromosomal protein HMG-14-like. | 0.611 |
Hmgb2-2 | Hmgn2 | ENSRNOP00000039358 | ENSRNOP00000074978 | High mobility group box 2-like 1. | Non-histone chromosomal protein HMG-17; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity). | 0.480 |
Hmgn1 | Cdhr5 | ENSRNOP00000067432 | ENSRNOP00000044906 | Non-histone chromosomal protein HMG-14-like. | Cadherin-related family member 5; Intermicrovillar adhesion molecule that forms, via its extracellular domain, calcium-dependent heterophilic complexes with CDHR2 on adjacent microvilli. Thereby, controls the packing of microvilli at the apical membrane of epithelial cells. Through its cytoplasmic domain, interacts with microvillus cytoplasmic proteins to form the intermicrovillar adhesion complex/IMAC. This complex plays a central role in microvilli and epithelial brush border differentiation. | 0.437 |
Hmgn1 | H2az2 | ENSRNOP00000067432 | ENSRNOP00000073832 | Non-histone chromosomal protein HMG-14-like. | Histone H2A; Belongs to the histone H2A family. | 0.417 |
Hmgn1 | Hmgb2 | ENSRNOP00000067432 | ENSRNOP00000017635 | Non-histone chromosomal protein HMG-14-like. | High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes (By similarity). Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor bindi [...] | 0.590 |
Hmgn1 | Hmgb2-2 | ENSRNOP00000067432 | ENSRNOP00000039358 | Non-histone chromosomal protein HMG-14-like. | High mobility group box 2-like 1. | 0.611 |
Hmgn1 | Hmgn2 | ENSRNOP00000067432 | ENSRNOP00000074978 | Non-histone chromosomal protein HMG-14-like. | Non-histone chromosomal protein HMG-17; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity). | 0.716 |
Hmgn1 | Hmgn5b | ENSRNOP00000067432 | ENSRNOP00000047671 | Non-histone chromosomal protein HMG-14-like. | High mobility group nucleosome-binding domain-containing protein 5; Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction. | 0.571 |
Hmgn1 | Igsf1 | ENSRNOP00000067432 | ENSRNOP00000010325 | Non-histone chromosomal protein HMG-14-like. | Immunoglobulin superfamily member 1; Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription (By similarity). | 0.487 |
Hmgn1 | Smpdl3a | ENSRNOP00000067432 | ENSRNOP00000001081 | Non-histone chromosomal protein HMG-14-like. | Acid sphingomyelinase-like phosphodiesterase 3a; Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP. Has in vitro activity with p- nitrophenyl-TMP. Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates. Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine. Does not have sphingomyelin phosphodiesterase activity. | 0.421 |
Hmgn1 | Tlr4 | ENSRNOP00000067432 | ENSRNOP00000014020 | Non-histone chromosomal protein HMG-14-like. | Toll-like receptor 4; Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate. In complex with TLR6, promotes sterile inflammation in monocytes/macrophages in response to oxidized low-density lipoprotein (oxLDL) or amyloid-beta 42. In this context, the initial signal is provided by oxLDL- or amyloid-beta 42-binding to [...] | 0.469 |
Hmgn2 | Hmgb2 | ENSRNOP00000074978 | ENSRNOP00000017635 | Non-histone chromosomal protein HMG-17; Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity). | High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. In the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and probably other processes (By similarity). Binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters by enhancing transcription factor bindi [...] | 0.560 |