STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem37Voltage-dependent calcium channel gamma-like subunit; Thought to stabilize the calcium channel in an inactivated (closed) state. Modulates calcium current when coexpressed with CACNA1G (By similarity). (209 aa)    
Predicted Functional Partners:
Jmjd1c
Jumonji domain-containing 1C.
      
 0.842
Prl3d2
Prolactin family 3, subfamily d, member 2.
      
 0.645
Ankrd23
Ankyrin repeat domain 23.
      
 0.562
Fam102b
Family with sequence similarity 102, member B.
      
 0.550
Ankrd39
Ankyrin repeat domain 39.
      
 0.534
Sctr
Secretin receptor; Receptor for secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Upon binding to secretin, regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (By similarity). In addition to regulating the pH of the duodenal content, plays [...]
   
  
 0.526
Prl3d1
Prolactin-3D1; Belongs to the somatotropin/prolactin family.
   
  
 0.524
Crisp2
Cysteine-rich secretory protein 2; Belongs to the CRISP family.
      
 0.499
Crisp1
Cysteine-rich secretory protein 1.
      
 0.499
Ttc39c
Tetratricopeptide repeat protein 39C; Belongs to the TTC39 family.
      
 0.473
Your Current Organism:
Rattus norvegicus
NCBI taxonomy Id: 10116
Other names: Buffalo rat, Norway rat, R. norvegicus, Rattus PC12 clone IS, Rattus sp. strain Wistar, Sprague-Dawley rat, Wistar rats, brown rat, laboratory rat, rat, rats, zitter rats
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