STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hpgd15-hydroxyprostaglandin dehydrogenase [NAD(+)]; Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4 (By similarity); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)    
Predicted Functional Partners:
HSDL2
Hydroxysteroid dehydrogenase like 2.
  
 0.876
PTGES
Prostaglandin E synthase.
     
 0.828
ALDH7A1
Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.
  
 0.823
ECHS1
Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.821
LOC100719714
Uncharacterized protein.
  
  
0.818
HADHA
Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.813
HIBCH
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
   
 0.813
ACOX3
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
  
 0.809
AACS
Acetoacetyl-CoA synthetase.
    
 0.795
HPGDS
Hematopoietic prostaglandin D synthase.
   
 0.774
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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