STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRKCRK proto-oncogene, adaptor protein. (281 aa)    
Predicted Functional Partners:
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.997
CBL
Cbl proto-oncogene.
    
 0.996
ABL2
Tyrosine-protein kinase.
    
 0.991
ABL1
Tyrosine-protein kinase.
    
 0.988
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.988
RAPGEF1
Rap guanine nucleotide exchange factor 1.
    
 0.987
DOCK1
Dedicator of cytokinesis 1; Belongs to the DOCK family.
    
 0.986
ELMO1
Engulfment and cell motility 1.
    
 0.974
FRS2
Fibroblast growth factor receptor substrate 2.
    
 0.973
ELMO2
Engulfment and cell motility 2.
    
 0.972
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.