ERG protein (Cavia porcellus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

ERG

ETS transcription factor ERG. (486 aa)

Predicted Functional Partners:

RUNX1

0.719

RUNX2

0.719

RUNX3

0.719

H0VHS7_CAVPO

0.684

TAL1

0.645

SPI1

0.645

SRF

0.645

AR

0.619

MYB

0.607

Spib

0.571

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	ERG	ENSCPOP00000015421	ENSCPOP00000006752	Androgen receptor.	ETS transcription factor ERG.	0.619
AR	RUNX1	ENSCPOP00000015421	ENSCPOP00000021315	Androgen receptor.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.683
AR	RUNX2	ENSCPOP00000015421	ENSCPOP00000026571	Androgen receptor.	RUNX family transcription factor 2.	0.713
AR	RUNX3	ENSCPOP00000015421	ENSCPOP00000030407	Androgen receptor.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.683
ERG	AR	ENSCPOP00000006752	ENSCPOP00000015421	ETS transcription factor ERG.	Androgen receptor.	0.619
ERG	H0VHS7_CAVPO	ENSCPOP00000006752	ENSCPOP00000009720	ETS transcription factor ERG.	Uncharacterized protein.	0.684
ERG	MYB	ENSCPOP00000006752	ENSCPOP00000013161	ETS transcription factor ERG.	MYB proto-oncogene, transcription factor.	0.607
ERG	RUNX1	ENSCPOP00000006752	ENSCPOP00000021315	ETS transcription factor ERG.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.719
ERG	RUNX2	ENSCPOP00000006752	ENSCPOP00000026571	ETS transcription factor ERG.	RUNX family transcription factor 2.	0.719
ERG	RUNX3	ENSCPOP00000006752	ENSCPOP00000030407	ETS transcription factor ERG.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.719
ERG	SPI1	ENSCPOP00000006752	ENSCPOP00000015005	ETS transcription factor ERG.	Spi-1 proto-oncogene.	0.645
ERG	SRF	ENSCPOP00000006752	ENSCPOP00000015471	ETS transcription factor ERG.	Serum response factor.	0.645
ERG	Spib	ENSCPOP00000006752	ENSCPOP00000031814	ETS transcription factor ERG.	ETS domain-containing protein.	0.571
ERG	TAL1	ENSCPOP00000006752	ENSCPOP00000003215	ETS transcription factor ERG.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.645
H0VHS7_CAVPO	ERG	ENSCPOP00000009720	ENSCPOP00000006752	Uncharacterized protein.	ETS transcription factor ERG.	0.684
H0VHS7_CAVPO	RUNX1	ENSCPOP00000009720	ENSCPOP00000021315	Uncharacterized protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.972
H0VHS7_CAVPO	RUNX2	ENSCPOP00000009720	ENSCPOP00000026571	Uncharacterized protein.	RUNX family transcription factor 2.	0.978
H0VHS7_CAVPO	RUNX3	ENSCPOP00000009720	ENSCPOP00000030407	Uncharacterized protein.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.972
H0VHS7_CAVPO	TAL1	ENSCPOP00000009720	ENSCPOP00000003215	Uncharacterized protein.	TAL bHLH transcription factor 1, erythroid differentiation factor.	0.753
MYB	ERG	ENSCPOP00000013161	ENSCPOP00000006752	MYB proto-oncogene, transcription factor.	ETS transcription factor ERG.	0.607