SHD protein (Cavia porcellus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SHD

Src homology 2 domain containing transforming protein D. (345 aa)

Predicted Functional Partners:

SLC6A12

0.565

POPDC3

0.512

ROCK1

0.479

ROCK2

0.479

CYFIP2

0.457

YES1

0.431

SRC

0.431

KDR

0.418

ITK

0.412

CLDN10

0.405

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN10	SHD	ENSCPOP00000027649	ENSCPOP00000007281	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Src homology 2 domain containing transforming protein D.	0.405
CLDN10	SLC6A12	ENSCPOP00000027649	ENSCPOP00000023112	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.405
CYFIP2	SHD	ENSCPOP00000022054	ENSCPOP00000007281	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Src homology 2 domain containing transforming protein D.	0.457
CYFIP2	SRC	ENSCPOP00000022054	ENSCPOP00000021377	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Tyrosine-protein kinase.	0.623
CYFIP2	YES1	ENSCPOP00000022054	ENSCPOP00000014047	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	Tyrosine-protein kinase.	0.623
ITK	SHD	ENSCPOP00000009249	ENSCPOP00000007281	Tyrosine-protein kinase.	Src homology 2 domain containing transforming protein D.	0.412
ITK	SRC	ENSCPOP00000009249	ENSCPOP00000021377	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.771
ITK	YES1	ENSCPOP00000009249	ENSCPOP00000014047	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.763
KDR	ROCK1	ENSCPOP00000008975	ENSCPOP00000009405	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.533
KDR	ROCK2	ENSCPOP00000008975	ENSCPOP00000011391	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.545
KDR	SHD	ENSCPOP00000008975	ENSCPOP00000007281	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Src homology 2 domain containing transforming protein D.	0.418
KDR	SRC	ENSCPOP00000008975	ENSCPOP00000021377	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Tyrosine-protein kinase.	0.900
KDR	YES1	ENSCPOP00000008975	ENSCPOP00000014047	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Tyrosine-protein kinase.	0.900
POPDC3	SHD	ENSCPOP00000029534	ENSCPOP00000007281	Popeye domain containing 3.	Src homology 2 domain containing transforming protein D.	0.512
POPDC3	SLC6A12	ENSCPOP00000029534	ENSCPOP00000023112	Popeye domain containing 3.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.509
ROCK1	KDR	ENSCPOP00000009405	ENSCPOP00000008975	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.533
ROCK1	ROCK2	ENSCPOP00000009405	ENSCPOP00000011391	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.942
ROCK1	SHD	ENSCPOP00000009405	ENSCPOP00000007281	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Src homology 2 domain containing transforming protein D.	0.479
ROCK1	SRC	ENSCPOP00000009405	ENSCPOP00000021377	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Tyrosine-protein kinase.	0.598
ROCK1	YES1	ENSCPOP00000009405	ENSCPOP00000014047	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Tyrosine-protein kinase.	0.565