STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pitx2Homeobox protein. (325 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta 1.
    
 
 0.784
PITX3
Homeobox protein.
  
 
  
0.676
FOXC2
Forkhead box C2.
    
 
 0.553
POU1F1
POU domain protein.
   
 
 0.545
LEF1
Lymphoid enhancer binding factor 1.
    
 
 0.484
Lefty2
TGF_BETA_2 domain-containing protein.
   
  
 0.481
LHX4
LIM homeobox 4.
   
  
 0.471
OSR2
Odd-skipped related transciption factor 2.
    
 
 0.431
CYP1B1
Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.
      
 0.431
PAX9
Paired box 9.
   
  
 0.421
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.