STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LTA4HLeukotriene A-4 hydrolase; Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. (611 aa)    
Predicted Functional Partners:
LTC4S
Leukotriene C4 synthase; Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4; Belongs to the MAPEG family.
     
 0.947
ALOX5
Arachidonate 5-lipoxygenase.
     
 0.925
CYP4F8
Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family.
    
 0.913
TRIT1
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37; Belongs to the IPP transferase family.
      0.888
ALOX12
Arachidonate 12-lipoxygenase, 12S type.
     
 0.876
LOC100733735
Uncharacterized protein; Belongs to the cytochrome P450 family.
    
 0.754
LOC100719677
Uncharacterized protein.
     
 0.684
CYP4F22
Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family.
    
 0.681
ALOX5AP
Arachidonate 5-lipoxygenase activating protein.
      
 0.677
CNDP2
Carnosine dipeptidase 2.
 
 0.664
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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