STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRERF1Transcriptional regulating factor 1. (1185 aa)    
Predicted Functional Partners:
DNTTIP1
Deoxynucleotidyltransferase terminal interacting protein 1.
    
 
 0.841
ELMSAN1
ELM2 and Myb/SANT domain containing 1.
    
 
0.704
KCTD19
Potassium channel tetramerization domain containing 19.
      
 0.628
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
    
 
 0.602
APBB2
Amyloid beta precursor protein binding family B member 2.
      
 0.550
THAP5
THAP domain containing 5.
  
 
   0.526
BTBD8
BTB domain containing 8.
  
     0.513
CLUL1
Clusterin; Belongs to the clusterin family.
  
     0.495
P2RY11
Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family.
  
   
 0.468
ZNF862
Zinc finger protein 862.
  
 
   0.463
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.