Cfb protein (Cavia porcellus) - STRING interaction network

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Score

Cfb

Uncharacterized protein; Belongs to the peptidase S1 family. (766 aa)

Predicted Functional Partners:

C3

0.966

CFD

0.954

SERPING1

0.890

LOC100728345

0.885

CFP

0.860

Masp2

0.849

GZMK

0.843

H0W7A0_CAVPO

0.818

C1QB

0.815

C1QA

0.814

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1QA	C1QB	ENSCPOP00000031712	ENSCPOP00000007305	Complement C1q A chain.	Complement C1q B chain.	0.998
C1QA	C3	ENSCPOP00000031712	ENSCPOP00000018087	Complement C1q A chain.	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	0.844
C1QA	Cfb	ENSCPOP00000031712	ENSCPOP00000014382	Complement C1q A chain.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.814
C1QA	H0W7A0_CAVPO	ENSCPOP00000031712	ENSCPOP00000018854	Complement C1q A chain.	NTR domain-containing protein.	0.731
C1QA	LOC100728345	ENSCPOP00000031712	ENSCPOP00000022343	Complement C1q A chain.	Anaphylatoxin-like domain-containing protein.	0.927
C1QA	Masp2	ENSCPOP00000031712	ENSCPOP00000010454	Complement C1q A chain.	CUB domain-containing protein.	0.730
C1QA	SERPING1	ENSCPOP00000031712	ENSCPOP00000024504	Complement C1q A chain.	SERPIN domain-containing protein; Belongs to the serpin family.	0.901
C1QB	C1QA	ENSCPOP00000007305	ENSCPOP00000031712	Complement C1q B chain.	Complement C1q A chain.	0.998
C1QB	C3	ENSCPOP00000007305	ENSCPOP00000018087	Complement C1q B chain.	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	0.735
C1QB	Cfb	ENSCPOP00000007305	ENSCPOP00000014382	Complement C1q B chain.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.815
C1QB	H0W7A0_CAVPO	ENSCPOP00000007305	ENSCPOP00000018854	Complement C1q B chain.	NTR domain-containing protein.	0.716
C1QB	LOC100728345	ENSCPOP00000007305	ENSCPOP00000022343	Complement C1q B chain.	Anaphylatoxin-like domain-containing protein.	0.921
C1QB	Masp2	ENSCPOP00000007305	ENSCPOP00000010454	Complement C1q B chain.	CUB domain-containing protein.	0.659
C1QB	SERPING1	ENSCPOP00000007305	ENSCPOP00000024504	Complement C1q B chain.	SERPIN domain-containing protein; Belongs to the serpin family.	0.919
C3	C1QA	ENSCPOP00000018087	ENSCPOP00000031712	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Complement C1q A chain.	0.844
C3	C1QB	ENSCPOP00000018087	ENSCPOP00000007305	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Complement C1q B chain.	0.735
C3	CFD	ENSCPOP00000018087	ENSCPOP00000005660	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Complement factor D; Belongs to the peptidase S1 family.	0.878
C3	CFP	ENSCPOP00000018087	ENSCPOP00000006537	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Properdin; A positive regulator of the alternate pathway of complement (By similarity). It binds to and stabilizes the C3- and C5-convertase enzyme complexes (By similarity). Inhibits CFI-CFH mediated degradation of Inhibits CFI-CFH mediated degradation of Complement C3 beta chain (C3b) (By similarity).	0.974
C3	Cfb	ENSCPOP00000018087	ENSCPOP00000014382	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.966
C3	GZMK	ENSCPOP00000018087	ENSCPOP00000007255	Complement C3c alpha' chain fragment 1; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. [C3-beta-c]: Acts as a chemoattractant for neutrophils in chronic inflammation.	Granzyme K; Belongs to the peptidase S1 family.	0.725