STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARL14EPLADP ribosylation factor like GTPase 14 effector protein like. (152 aa)    
Predicted Functional Partners:
ATF7IP
Activating transcription factor 7 interacting protein.
    
 
 0.800
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
    
 
 0.775
SETDB2
SET domain bifurcated histone lysine methyltransferase 2.
    
 
 0.775
H0V482_CAVPO
Uncharacterized protein.
    
 
 0.754
SUOX
Sulfite oxidase.
      
 0.605
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
   0.530
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
   0.530
MED21
Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
    0.448
TMEM65
Transmembrane protein 65.
   
  
 0.408
SUV39H2
Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
    
 
 0.406
Your Current Organism:
Cavia porcellus
NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig
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