ARHGAP10 protein (Cavia porcellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ARHGAP10

Rho GTPase activating protein 10. (750 aa)

Predicted Functional Partners:

BRK1

0.923

ACTB

0.916

ACTG1

0.916

NCKAP1L

0.878

NCKAP1

0.878

CYFIP2

0.876

CYFIP1

0.876

WASF1

0.854

WASF3

0.854

WASF2

0.854

Your Current Organism:

Cavia porcellus

NCBI taxonomy Id: 10141
Other names: C. porcellus, Cavia aperea porcellus, Cavia cobaya, domestic guinea pig, guinea pig

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTG1	ENSCPOP00000022236	ENSCPOP00000030661	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Actin gamma 1.	0.909
ACTB	ARHGAP10	ENSCPOP00000022236	ENSCPOP00000029094	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Rho GTPase activating protein 10.	0.916
ACTB	BRK1	ENSCPOP00000022236	ENSCPOP00000029253	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	BRICK1 subunit of SCAR/WAVE actin nucleating complex.	0.556
ACTB	CYFIP1	ENSCPOP00000022236	ENSCPOP00000024210	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.521
ACTB	CYFIP2	ENSCPOP00000022236	ENSCPOP00000022054	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.528
ACTB	NCKAP1	ENSCPOP00000022236	ENSCPOP00000015030	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	NCK associated protein 1.	0.538
ACTB	NCKAP1L	ENSCPOP00000022236	ENSCPOP00000007853	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	NCK associated protein 1 like.	0.538
ACTB	WASF1	ENSCPOP00000022236	ENSCPOP00000003690	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	WASP family member 1.	0.937
ACTB	WASF2	ENSCPOP00000022236	ENSCPOP00000023672	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	WASP family member 2.	0.942
ACTB	WASF3	ENSCPOP00000022236	ENSCPOP00000009121	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	WASP family member 3.	0.727
ACTG1	ACTB	ENSCPOP00000030661	ENSCPOP00000022236	Actin gamma 1.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.909
ACTG1	ARHGAP10	ENSCPOP00000030661	ENSCPOP00000029094	Actin gamma 1.	Rho GTPase activating protein 10.	0.916
ACTG1	BRK1	ENSCPOP00000030661	ENSCPOP00000029253	Actin gamma 1.	BRICK1 subunit of SCAR/WAVE actin nucleating complex.	0.556
ACTG1	CYFIP1	ENSCPOP00000030661	ENSCPOP00000024210	Actin gamma 1.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.521
ACTG1	CYFIP2	ENSCPOP00000030661	ENSCPOP00000022054	Actin gamma 1.	Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.	0.528
ACTG1	NCKAP1	ENSCPOP00000030661	ENSCPOP00000015030	Actin gamma 1.	NCK associated protein 1.	0.538
ACTG1	NCKAP1L	ENSCPOP00000030661	ENSCPOP00000007853	Actin gamma 1.	NCK associated protein 1 like.	0.538
ACTG1	WASF1	ENSCPOP00000030661	ENSCPOP00000003690	Actin gamma 1.	WASP family member 1.	0.937
ACTG1	WASF2	ENSCPOP00000030661	ENSCPOP00000023672	Actin gamma 1.	WASP family member 2.	0.942
ACTG1	WASF3	ENSCPOP00000030661	ENSCPOP00000009121	Actin gamma 1.	WASP family member 3.	0.727