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hisI protein (Rhodococcus jostii) - STRING interaction network
"hisI" - Protein involved in phosphoribosyl-ATP diphosphatase activity and histidine biosynthesis in Rhodococcus jostii
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisIProtein involved in phosphoribosyl-ATP diphosphatase activity and histidine biosynthesis (93 aa)    
Predicted Functional Partners:
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Long subfamily (283 aa)
 
 
  0.996
hisI2
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (114 aa)
 
   
  0.973
metH
Methionine synthase; Protein involved in dihydropteroate synthase activity, methionine synthase activity, homocysteine S-methyltransferase activity, cobalt ion binding, methionine biosynthesis and folic acid and derivative biosynthesis (1189 aa)
         
  0.935
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Protein involved in 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase activity, phosphoribosylanthranilate isomerase activity, histidine biosynthesis and tryptophan biosynthesis (244 aa)
 
   
  0.888
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (257 aa)
 
   
  0.886
hisD1
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (440 aa)
 
   
  0.855
hisB
annotation not available (204 aa)
 
   
  0.841
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (211 aa)
 
   
  0.826
ABG92691.1
Possible hydrolase; Protein involved in methyltransferase activity, oxidoreductase activity, hydrolase activity and metabolism (230 aa)
              0.813
ABG92689.1
Protein involved in RNA binding, pseudouridylate synthase activity, pseudouridine synthase activity and tRNA processing (297 aa)
              0.783
Your Current Organism:
Rhodococcus jostii
NCBI taxonomy Id: 101510
Other names: R. jostii RHA1, Rhodococcus jostii, Rhodococcus jostii RHA1, Rhodococcus jostii str. RHA1, Rhodococcus jostii strain RHA1, Rhodococcus sp. (strain RHA1), Rhodococcus sp. RHA1
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