STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX58Putative ATP-dependent RNA helicase DDX58. (925 aa)    
Predicted Functional Partners:
Mavs
Mitochondrial antiviral-signaling protein.
    
 0.999
Trim25
Tripartite motif-containing protein 25.
   
 0.996
Dhx58
Putative ATP-dependent RNA helicase DHX58.
   
0.988
Atg12
Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.
    
 0.973
ATG5
Autophagy protein 5; Involved in autophagic vesicle formation.
    
 0.973
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.945
Rnf125
E3 ubiquitin-protein ligase RNF125.
    
 0.944
GW7_08155
RING finger protein 135.
   
 0.940
Eif2ak2
Interferon-induced, double-stranded RNA-activated protein kinase.
   
 0.939
Cyld
Putative ubiquitin carboxyl-terminal hydrolase CYLD.
    
 0.935
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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