STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCL2L1Bcl-2-like protein 1 isoform 2. (233 aa)    
Predicted Functional Partners:
Bcl2l11
Bcl-2-like protein 11.
    
 0.999
BAK1
Putative Bcl-2-like protein antagonist/killer 2.
    
0.997
GW7_20676
Bcl2 antagonist of cell death.
   
 0.995
Bid
BH3-interacting domain death agonist.
   
 0.995
Bad
Bcl2 antagonist of cell death.
   
 0.994
Bbc3
Bcl-2-binding component 3.
   
 0.992
Bcl2
Apoptosis regulator Bcl-2.
    
0.992
GW7_12872
Beclin-1-like protein 1.
    
 0.983
Tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.970
Bnip3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.
    
 0.969
Your Current Organism:
Heterocephalus glaber
NCBI taxonomy Id: 10181
Other names: H. glaber, naked mole rat, naked mole-rat
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.