STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BpHYR1_0145122-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (606 aa)    
Predicted Functional Partners:
BpHYR1_050292
2-oxoisovalerate dehydrogenase subunit mitochondrial.
 
 0.998
BpHYR1_049335
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.996
BpHYR1_051912
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.990
BpHYR1_041095
Dihydrolipoyl dehydrogenase.
  
 
 0.970
BpHYR1_048940
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.969
BpHYR1_025268
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.966
BpHYR1_016792
annotation not available
  
 0.959
BpHYR1_028444
Thioredoxin reductase 3; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 
 0.958
BpHYR1_002404
Glutamate mitochondrial; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.949
BpHYR1_026406
Hydroxymethylglutaryl-mitochondrial.
  
 
 0.908
Your Current Organism:
Brachionus plicatilis
NCBI taxonomy Id: 10195
Other names: B. plicatilis
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