STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CIAO1_TRIADProbable cytosolic iron-sulfur protein assembly protein CIAO1 homolog; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (313 aa)    
Predicted Functional Partners:
B3RVK4_TRIAD
FeS_assembly_P domain-containing protein.
    
 0.999
B3S351_TRIAD
Uncharacterized protein.
    
 0.993
B3SC06_TRIAD
Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family.
    
 0.961
B3RT11_TRIAD
FeS_assembly_P domain-containing protein.
    
 0.957
B3S4G2_TRIAD
NIF3-like protein 1; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
 
    
 0.854
B3RYU5_TRIAD
Helicase ATP-binding domain-containing protein.
    
 0.793
DRE2_TRIAD
Anamorsin homolog; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex. Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase. Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RN [...]
      
 0.779
NUBP2_TRIAD
Cytosolic Fe-S cluster assembly factor NUBP2 homolog; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
 
 
 0.697
B3S8G2_TRIAD
Uncharacterized protein.
      
 0.630
B3RMK9_TRIAD
Uncharacterized protein.
 
 
 0.594
Your Current Organism:
Trichoplax adhaerens
NCBI taxonomy Id: 10228
Other names: T. adhaerens
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